Results 111 to 120 of about 6,378 (227)

Non-invasive prenatal testing for chromosomal aneuploidies

, 2017
The aim of this literature review is to give an overview of the conventional screening methods currently utilized for prenatal detection of chromosomal abnormalities and the development of non-invasive prenatal testing (NIPT) starting with the original ...
Joseph, Hazel Kristine
core  

Motivations for accepting/declining NIPT; most important test attribute for NIPT accepters; reasons why women declined DSS in a previous pregnancy.

, 2016
Motivations for accepting/declining NIPT; most important test attribute for NIPT accepters; reasons why women declined DSS in a previous pregnancy.
Celine Lewis (2591242), Lyn S. Chitty (135435), Melissa Hill (548604)   +2 more
core   +1 more source

Delineating the Scope of NIPT: Ethics Meets Practice

The American Journal of Bioethics, 2022
openaire   +2 more sources

Strategies to Detect Chromosomal Anomalies Not Identified by NIPT

Prenatal Diagnosis
ABSTRACTIntroductionGenome‐wide non‐invasive prenatal testing (gwNIPT) has screening limitations for detectable chromosomal conditions and cannot detect microdeletions/microduplications (MD) or triploidy. Thickened nuchal translucency (NT) only detects around 10% of these cases.MethodsA 4‐year retrospective study of singleton pregnancies undergoing ...
Fergus Scott, May Phoo Han, Ana Elizabeth Gomes de Melo Tavares Ferreira, James Elhindi, Andrew C. McLennan   +4 more
openaire   +2 more sources

Views and attitudes about the offer of NIPT: a qualitative study of UK healthcare professionals

BMC Medical Ethics
Background Healthcare professionals have ethical duties to provide information according to conceptions of the doctor-patient relationship, and one way this responsibility is established in practice is by UK guidance on shared decision making.
Peter D. Young, Katherine M. Sahan
doaj   +1 more source

Noninvasive prenatal testing for the detection of fetal chromosome 17 microduplication: clinical implications and findings

Molecular Cytogenetics
Background  Noninvasive prenatal testing (NIPT) is widely used to screen for fetal aneuploidies. However, there are few reports of using NIPT for screening chromosomal microduplications and microdeletions.
Ye Shi, Fang-xiu Zheng, Jing Wang, Qin Zhou, Ying-ping Chen, Bin Zhang   +5 more
doaj   +1 more source

Oligonukleotidiraaka-aineen puhtauden optimointi Vanadis NIPT Assay analyysille

, 2023
Kromosomaalisten sairauksien seulonta on osa kansallisia raskaudenaikaisia tutkimuksia. Seulontojen tarkoitus on tunnistaa kromosomipoikkeavuudet sikiönkehityksen alkuvaiheessa, ja siten helpottaa hoitopäätösten tekoa.
Sihvonen, Sanni
core  

One-way sensitivity analysis of contingent NIPT vs MSS from a government perspective.

, 2015
Below are the one-way sensitivity analysis results of ICER between contingent NIPT and MSS. Contingent NIPT is less costly than MSS as long as the cost of NIPT remains below $663.
Richard E. Nelson (764526), Brian R. Jackson (233567), Edward R. Ashwood (764528), David G. Grenache (764527), Brandon S. Walker (764525), Robert L. Schmidt (764529)   +5 more
core   +1 more source

5. NIPT in Germany

, 2022
Kathrin Braun, Sabine Könninger
openaire   +1 more source

Should the scope of NIPT be limited by a ‘threshold of seriousness’?

European Journal of Human Genetics
Abstract Non-invasive prenatal testing (NIPT) has the potential to screen for a wider range of genetic conditions than is currently possible at an early stage of pregnancy and with minimal risks. As such, there have been calls to apply a ‘threshold of seriousness’ to limit the scope of conditions being tested.
Michelle Taylor-Sands, Molly Johnston, Catherine Mills   +2 more
openaire   +2 more sources