Results 91 to 100 of about 6,510 (202)

Omicron SARS-CoV-2 infection management and outcomes in patients with hematologic disease and recipients of cell therapy [PDF]

open access: yes
Introduction: Scarce real-life data exists for COVID-19 management in hematologic disease (HD) patients in the Omicron era. Purpose: To assess the current clinical management and outcome of SARS-CoV-2 infection diagnosed, identify the risk factors for ...
Aiello, Tommaso Francesco   +30 more
core   +1 more source

Sequential or Combination Treatments as Rescue Therapies in Immunocompromised Patients with Persistent SARS-CoV-2 Infection in the Omicron Era: A Case Series [PDF]

open access: yes, 2023
Bonora, Stefano   +7 more
core   +1 more source

An Intersectional Analysis of Social Deprivation and Patient Characteristics on Nirmatrelvir-Ritonavir for Treatment of COVID-19 in U.S. Primary Care Practices, 2021 to 2023

open access: yesJournal of Primary Care & Community Health
Objective: Calculate rates of nirmatrelvir-ritonavir prescription and assess area-level social deprivation as an effect modifier of patient characteristics on nirmatrelvir-ritonavir for the treatment of COVID-19.
Esther E. Velásquez   +5 more
doaj   +1 more source

Clinical real-world effectiveness of nirmatrelvir/ritonavir for the treatment of SARS-CoV-2 infection: A meta-analysis

open access: yesTungs’ Medical Journal
Background: According to the Evaluation of Protease Inhibition for COVID-19 in High-Risk Patients (EPIC-HR) study, compared with a placebo, nirmatrelvir/ritonavir significantly reduced the risk of coronavirus disease 2019 (COVID-19)-related ...
Chienhsiu Huang, Sufang Kuo, Lichen Lin
doaj   +1 more source

SARS-CoV-2 genomic evolution during a severe and long-lasting omicron infection under antiviral therapy [PDF]

open access: yes
BackgroundProlonged SARS-CoV-2 infection observed in immunocompromised individuals even in the presence of antiviral treatment provides opportunities for viruses to evolve in immune escape and drug-resistant variants.Case presentationA 72-year-old male ...
Alagna, Laura   +10 more
core   +1 more source

Patterns of use of oral antivirals for COVID-19 in people 70 years and over in Victoria, Australia: a linked data study

open access: yesBMC Infectious Diseases
Background Two oral antivirals for treatment of COVID-19 are available in Australia, nirmatrelvir-ritonavir, which is recommended, and molnupiravir, which is approved for use when nirmatrelvir-ritonavir is contraindicated.
Laura J. Edwards   +6 more
doaj   +1 more source

ORCHESTRA Delphi consensus: diagnostic and therapeutic management of SARS-CoV-2 infection in solid organ transplant recipients [PDF]

open access: yes
Objectives: We aimed to address existing knowledge gaps regarding risk stratification, best use of diagnostic resources, optimal treatment, and general management of SARS-CoV-2 infection in solid organ transplant (SOT) recipients.
Tazza, Beatrice   +14 more
core   +2 more sources

Successful use of nirmatrelvir/ritonavir in immunocompromised patients with persistent and/or relapsing COVID-19 [PDF]

open access: yes, 2023
Bartoloni, Alessandro   +14 more
core   +1 more source

Clinical Effectiveness of Ritonavir-Boosted Nirmatrelvir—A Literature Review

open access: yesAdvances in Respiratory Medicine
Nirmatrelvir/Ritonavir is an oral treatment for mild to moderate COVID-19 cases with a high risk for a severe course of the disease. For this paper, a comprehensive literature review was performed, leading to a summary of currently available data on ...
Sydney Paltra, Tim O. F. Conrad
doaj   +1 more source

ORCHESTRA Delphi consensus: clinical management of SARS-CoV-2 infection in people with HIV [PDF]

open access: yes
Objectives: The interaction between HIV and COVID-19 resulted in a syndemic that showed an excess burden of disease for people with HIV (PWH). Four years of the COVID-19 pandemic have raised many unsolved questions about the optimal care of COVID-19 in ...
Alemán-Rodríguez, Aurora   +81 more
core   +1 more source

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