Results 61 to 70 of about 2,404 (154)

RSV Molecular Epidemiology Pre‐ and Post‐COVID‐19 Pandemic Periods in Seattle, Washington, USA

open access: yesInfluenza and Other Respiratory Viruses, Volume 20, Issue 10, October 2026.
ABSTRACT Background Globally, RSV declined to historically low levels following stay‐at‐home orders in 2020 and re‐emerged as restrictions lifted, with large inter‐seasonal outbreaks and other shifts in epidemiology. The effect of the pandemic restrictions on genomic diversity has not been well studied.
Pavitra Roychoudhury   +21 more
wiley   +1 more source

Real-world impact of nirsevimab on RSV hospitalizations in children under 2 years of age: retrospective monocentric study in a large German tertiary pedatric center

open access: yesMolecular and Cellular Pediatrics
Background Respiratory syncytial virus (RSV) infection is a leading cause of hospitalization among infants and young children. Broad immunization with the monoclonal antibody nirsevimab represents a promising preventive strategy. However, real-world data
Moritz Bauer   +4 more
doaj   +1 more source

Real-world emergence of nirsevimab resistance in breakthrough infections with respiratory syncytial virus-B: a multicentre observational study in France

open access: yesThe Lancet Microbe
Summary: Background: Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infection in infants. Nirsevimab, a long-acting monoclonal antibody targeting a conserved epitope on the prefusion F protein (site Φ), has shown high ...
ProfPhD Slim Fourati   +202 more
doaj   +1 more source

Impact of Nirsevimab immunoprophylaxis on professional exhaustion during two epidemics of respiratory syncytial virus [PDF]

open access: yes
Objective: We aimed to assess the impact of introducing immunoprophylaxis against respiratory syncytial virus in infants (healthy infants up to 6 months of age and vulnerable children up to 24 months) on the professional quality of life of pediatric ...
Castillo-Corullón, Silvia   +7 more
core   +1 more source

Cost-Effectiveness and Public Health Impact of Universal Prophylaxis with Nirsevimab Against Respiratory Syncytial Virus (RSV) Infections in all Infants in Japan

open access: yesInfectious Diseases and Therapy
Introduction Respiratory syncytial virus (RSV) is a common cause of lower respiratory tract disease, and the standard prevention strategy in Japan is limited to high-risk infants.
Shinichi Noto   +7 more
doaj   +1 more source

Efectividad de la inmunización con nirsevimab en neonatos para prevenir hospitalizaciones por virus respiratorio sincitial durante dos temporadas en Navarra

open access: yesAnales del Sistema Sanitario de Navarra
Fundamento. La infección por el virus respiratorio sincitial (VRS) es la principal causa de hospitalización en lactantes. En 2022 se autorizó el nirsevimab en la Unión Europea para prevenir la enfermedad respiratoria grave por VRS durante el primer año ...
Noelia Vera-Punzano   +11 more
doaj   +1 more source

RSV‐Pre‐F Vaccination During Pregnancy and Neonatal Outcomes—A Systematic Review and Meta‐Analysis

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 9, September 2026.
ABSTRACT Objectives Respiratory syncytial virus (RSV) is a major cause of infant morbidity and mortality worldwide. Recent preventive strategies include maternal vaccination and monoclonal antibodies. However, maternal RSV vaccination has raised safety concerns due to possible associations with preterm birth.
Niko Leskinen   +2 more
wiley   +1 more source

Effectiveness of nirsevimab immunization against RSV infection in preterm infants: a systematic review and meta-analysis

open access: yesFrontiers in Immunology
BackgroundRespiratory Syncytial Virus (RSV) is one of the primary pathogen responsible for severe lower respiratory tract infections in preterm infants, placing a significant burden on patients, their families, and society.
Xiaopeng Wang   +15 more
doaj   +1 more source

Estimating the National Disease Burden and Economic Burden of Respiratory Syncytial Virus (RSV) in Thailand

open access: yesInfluenza and Other Respiratory Viruses, Volume 20, Issue 9, September 2026.
ABSTRACT Background Respiratory syncytial virus (RSV), a single‐stranded negative‐sense RNA virus, causes respiratory tract infections in children and adults, leading to hospitalization and mortality. However, the national disease burden and economic impact of RSV in Thailand remain undetermined.
Kansak Boonpattharatthiti   +7 more
wiley   +1 more source

Lack of Differences in the Pharmacokinetics of Therapeutic Monoclonal Antibodies Between Japanese and Non‐Japanese Individuals

open access: yesThe Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta   +2 more
wiley   +1 more source

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