Results 41 to 50 of about 2,387 (195)

Vaccinations in pregnancy: An update for a changing time

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Maternal immunization is one of the most effective public health interventions to reduce infectious morbidity and mortality in pregnant women, fetuses, and newborns. Despite robust evidence supporting vaccine safety and effectiveness in pregnancy, global uptake has declined following the COVID‐19 pandemic, contributing to resurgent outbreaks ...
Wendy Hodge, Méabh Bhuinneáin, Gelila Goba, Marisa Labovsky, Eliana Amaral, Asma Khalil, David Lissauer, Hema Divakar, Fionnuala M. McAuliffe, Deborah Money, Dharmintra Pasupathy, on behalf of the FIGO Committee on Infections During Pregnancy   +11 more
wiley   +1 more source

Frequency, Burden and Pathogens of Acute Respiratory Illness in Very Preterm Infants During Infancy

Acta Paediatrica, EarlyView.
ABSTRACT Aim To describe the frequency, burden, and pathogen profile of acute respiratory illnesses (ARIs) in very preterm infants during the first year after neonatal intensive care unit (NICU) discharge. Methods Very preterm infants were followed prospectively (August 2015–January 2017) with monthly assessments of symptoms, medication use, and ...
Patricia De Gouveia Belinelo, Nada Townsi, Naomi R. Hemy, Chisha T. Sikazwe, David W. Smith, Benjamin Stoecklin, J. Jane Pillow, Graham L. Hall, Ingrid A. Laing, Shannon J. Simpson   +9 more
wiley   +1 more source

Respiratory Syncytial Virus Vaccination Is Associated With Increased Odds of Preterm Birth

Acta Paediatrica, Volume 115, Issue 11, Page 2473-2477, November 2026.
ABSTRACT Aim To analyse whether respiratory syncytial virus (RSV) vaccination during pregnancy increases the odds of preterm birth. Methods A rapid review and meta‐analysis was performed. The main outcome was the risk of preterm (gestational week less than 37) birth.
Ilari Kuitunen, Marjut Haapanen
wiley   +1 more source

Effectiveness of nirsevimab among infants in their first RSV season in the United States, October 2023–March 2024: a test-negative design analysisResearch in context

The Lancet Regional Health. Americas
Summary: Background: In August 2023, the Centers for Disease Control and Prevention recommended nirsevimab, a long-acting monoclonal antibody, for all U.S. infants aged
Amanda B. Payne, Steph Battan-Wraith, Elizabeth A.K. Rowley, Melissa S. Stockwell, Sara Y. Tartof, Kristin Dascomb, Stephanie A. Irving, Brian Dixon, Sarah W. Ball, Mark W. Tenforde, Gabriela Vazquez-Benitez, Ashley B. Stephens, Jungmi Han, Karthik Natarajan, S. Bianca Salas, Cassandra Bezi, Lina S. Sy, Bruno Lewin, Tamara Sheffield, Julie Arndorfer, Daniel Bride, Josh Van Otterloo, Allison L. Naleway, Padma D. Koppolu, Shaun Grannis, William Fadel, Colin Rogerson, Tom Duszynski, Sarah E. Reese, Patrick K. Mitchell, Sean Chickery, Heidi L. Moline, Morgan Najdowski, Allison Avrich Ciesla, Emily L. Reeves, Malini DeSilva, Katherine E. Fleming-Dutra, Ruth Link-Gelles   +37 more
doaj   +1 more source

Vaccinations During Pregnancy Protect the Mother–Infant Dyad and Are Generally Safe

Acta Paediatrica, Volume 115, Issue 11, Page 2380-2388, November 2026.
ABSTRACT Aim Vaccination in pregnancy has a critical impact on mothers, foetuses and infants. The aim of this paper was to summarise key points presented by experts attending the 12th Maria Delivoria‐Papadopoulos Perinatal Symposium in March 2025 and further expand and update them.
Ariadne Malamitsi‐Puchner, Despina D. Briana, Gian Carlo Di Renzo   +2 more
wiley   +1 more source

The New Era of Respiratory Syncytial Virus Protection for Infants: A Mini Review of Current Tools for Immunoprophylaxis

Acta Paediatrica, Volume 115, Issue 11, Page 2466-2472, November 2026.
ABSTRACT Aim This mini review describes the history of infant respiratory syncytial virus (RSV) immunoprophylaxis and the latest advances in this area. It also reviews the efficacy, safety and impact of the recently introduced prophylactic strategies. Method This narrative review is based on a targeted review of published literature, with emphasis on ...
Santtu Heinonen, Pekka Vartiainen
wiley   +1 more source

Optimal Respiratory Syncytial Virus intervention programmes using Nirsevimab in England and Wales [PDF]

, 2022
INTRODUCTION: Respiratory Syncytial Virus (RSV) is a major cause of acute lower respiratory tract infections (ALRI) in infants. There are no licensed vaccines and only one monoclonal antibody available to protect infants from disease.
Koltai, Mihaly, Flasche, Stefan, Jit, Mark, Atkins, Katherine E; id_orcid, Hodgson, David, Krauer, Fabienne, Atkins, Katherine E   +6 more
core   +1 more source

Potential for Nirsevimab use in Pakistan

Journal of the Pakistan Medical Association
Respiratory Tract Infections can be classified as upper and lower tract infections. Upper tract infections are more common such as laryngitis and pharyngitis, but the infections of lower respiratory tract are more fatal such as influenza or bronchitis.
Muhammad Moaz, Basum Hayat
openaire   +3 more sources

First real-world data on universal respiratory syncytial virus prophylaxis with Nirsevimab in infants [PDF]

Respiratory syncytial virus (RSV) predominantly affects young children, with a peak incidence in temperate regions of the northern hemisphere from October to May.
Scarpaleggia M., Rizzo C, Baldo V., Chironna M., Pariani E, Baldo V, Orsi A, Scarpaleggia M, Icardi G, Orsi A., Panatto D, Pariani E., Giuffrida S., Panatto D., Icardi G., Barbone F, Rizzo C., Giuffrida S, Barbone F., Montomoli E., Chironna M, Montomoli E   +20 more
core   +3 more sources

Pharmacokinetics, Immunogenicity, and Safety of a Modified YTE Antibody in Healthy Adults

Clinical Pharmacology in Drug Development, Volume 15, Issue 10, October 2026.
Abstract REGN17092, a fully human immunoglobulin (Ig) G1 antibody with M252Y/S254T/T256E (YTE) modification in the Fc portion, was assessed in a first‐in‐human study (ClinicalTrials.gov, NCT05923424). REGN17092 was designed to target the severe acute respiratory coronavirus 2 (SARS‐CoV‐2) S protein.
Maria Rosario, Jan de Hoon, Flonza Isa, Kenneth Turner, Jing Li, Joel Kantrowitz, Samit Ganguly, Sasha Fraser, Zhongqing Will He, Hong Yan, Ana Gonzalez Ortiz, Lori Faria, Ingeborg Heirman, Alina Baum, Thomas D Norton, Yogesh Patel, Veronica Mas Casullo, John D Davis   +17 more
wiley   +1 more source