Results 221 to 230 of about 558,186 (382)

Supersulfide biology and translational medicine for disease control

open access: yesBritish Journal of Pharmacology, EarlyView., 2023
Abstract For decades, the major focus of redox biology has been oxygen, the most abundant element on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial respiratory chain, contributing to energy production in aerobic organisms. In addition, oxygen‐derived reactive oxygen species including hydrogen peroxide and nitrogen
Uladzimir Barayeu   +5 more
wiley   +1 more source

Multi‐omics insights into surface charge effects to decode the interplay of nanoplastics and bacterial antibiotic resistance

open access: yesiMeta, EarlyView.
Multi‐omics approaches revealed how nanoplastics with different surface charges influence antibiotic resistance in Escherichia coli K12. Positively charged nanoplastics enhanced antibiotic resistance by upregulating genes and proteins linked to oxidative stress tolerance and efflux pumps, and promoted antibiotic resistance genes transfer via ...
Houyu Li, Yinuo Ding, Yan Xu, Wei Liu
wiley   +1 more source

Should the non‐canonical pathway of nitric oxide generation be targeted in hypertensive pregnancies?

open access: yesBritish Journal of Pharmacology, EarlyView., 2023
Abstract Hypertension in pregnancy is prevalent, affecting around 10% of pregnancies worldwide, and significantly increases the risk of adverse outcomes for both mothers and their babies. Current treatment strategies for pregnant women with hypertension are limited, and new approaches for the management of hypertension in pregnancy are urgently needed.
Elizabeth C. Cottrell
wiley   +1 more source

Deciphering the Toxicity of Metal Tungstates and Molybdates: Effects on L929 Cell Metabolic Activity, Oxidative Stress, and Genotoxicity

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT The increasing development and application of metal‐based materials in biomedical and environmental fields raise important concerns regarding their potential cytotoxic and genotoxic effects. Metal tungstates (MxWO4) and molybdates (MxMoO4) offer promising functional properties in health and environmental solutions but require safety validation
Marcelo Assis   +6 more
wiley   +1 more source

Growth but Not Corticosterone, Oxidative Stress, or Telomere Length Is Negatively Affected by Microplastic Exposure in a Filter‐Feeding Amphibian

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Microplastics (MPs) are of increasing global concern for species inhabiting aquatic habitats. However, the mechanisms behind animal responses to MPs still require comprehensive exploration. Amphibians are the most threatened vertebrate group with most species having a complex life cycle, commonly with an aquatic larval stage.
Colette Martin   +3 more
wiley   +1 more source

Genome-wide association study and BSR-seq identify nitrate reductase-related genes in rice landraces (Oryza sativa L.). [PDF]

open access: yesPlant Genome
Luo S   +17 more
europepmc   +1 more source

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