Results 191 to 200 of about 28,577 (254)

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

Advanced Science, EarlyView.
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu, Dandan Kou, Xiao Xiao, Bingbing Bai, Caide Liu, Mengyao Wu, Yadan Shi, Mengdan Xu, Xiaoyi Cao, Haodi Qi, Shuhua Wu, Jianfeng Zeng, Mingyuan Gao   +12 more
wiley   +1 more source

Dynamic Expression of the Type 1 Brugada ECG Pattern During Tilt Table Testing Using Continuous High Precordial Lead Positioning. [PDF]

Diagnostics (Basel)
Pereira ENS, Sacilotto L, Wu TC, Pessente GD, Pichara NL, Hachul DT, Scanavacca MI, Darrieux FCDC.   +7 more
europepmc   +1 more source

Maternal Exercise Rescues Embryonic Osteogenesis Impaired due to POLG Mutation Through a Potential Apelin‐ATF4 Axis

Advanced Science, EarlyView.
Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae, Ryan C. Riddle, Zhihua Jiang, Chaeyoung Shin, Min Du, Jun Seok Son   +5 more
wiley   +1 more source

Phylogenomic and metabolic insights into iron reduction metabolism in the genus <i>Deferribacter</i> belonging to the order <i>Deferribacterales</i>. [PDF]

Microb Genom
Pouder E, Alain K, Mieszkin S.
europepmc   +1 more source

Bio‐Based Polyurethanes for Sustainable and Multifunctional Applications

Advanced Science, EarlyView.
Bio‐based polyurethanes prepared from vegetable oils, lignin, and polysaccharides have attracted increasing interest as alternatives to fossil‐derived polyurethanes. This review summarizes recent progress in their chemistry, structural engineering, and advanced applications, highlighting the roles of feedstocks, chain‐segment design, dynamic covalent ...
Xin Li, Henghui Deng, Shiwei Yu, Jiawei Huang, Zehong Chen, Dawei Zhao, Chaoqun Zhang   +6 more
wiley   +1 more source

Impact of wildfires on soil microbial nutrient functions in Karst forest ecosystems. [PDF]

Front Microbiol
Fu Y, Li X, Li J, Liu X, Zhang Y, Zhang Y.   +5 more
europepmc   +1 more source

Livestock Multi‐Omics Integration: A Systematic Framework From Statistical Association to Causal Interpretation

Advanced Science, EarlyView.
A three‐tier livestock multi‐omics framework resolves four typical analytical pitfalls. Moving from statistical association through machine learning preprocessing to triple‐modal causal inference, it converts omics results into genomic selection and gene editing strategies to achieve One Health, underpinned by multi‐omics data, multimodal sequencing ...
Jiying Wen, Zhongyu Wang, Jieping Huang, Fen Li, Ningbo Chen, Yun Ma   +5 more
wiley   +1 more source

Phyllosphere of senescent crops as a microbial N₂O source. [PDF]

Front Microbiol
Tago K, Tokuda SI, Sato Y, Sekiyama Y, Guo Y, Wang Y, Date Y, Hara S, Kuroiwa M, Ohbayashi T, Aoyagi LN, Nishizawa T, Sudo S, Suwa Y, Hayatsu M.   +14 more
europepmc   +1 more source

Plaque‐Hepatic Targeting Nanotherapy Disrupts the PCSK9‐LOX‐1 Axis to Suppress oxLDL in Atherosclerosis

Advanced Science, EarlyView.
Self‑amplifying PCSK9–LOX‑1 feedback axis drives atherosclerotic progression by promoting oxLDL generation and endothelial uptake. A dual‑targeting nanoplatform (siPCSK9@PEAL NPs‑aL) is constructed to simultaneously silence hepatic PCSK9 for lipid lowering and block plaque LOX‑1 for anti‑inflammation.
Yi Duan, Yijie Qiu, Yan Zhu, Quan Wang, Jiangtao Lin, Yourong Duan, Qi Wang, Yi Dong   +7 more
wiley   +1 more source

Distinct Denitrification Phenotypes in Closely Related Bacteria: Clues to Understanding Variations in Nitrite Accumulation Among Stutzerimonas Strains. [PDF]

Environ Microbiol
Menestreau M, Milligan DA, Sennett LB, Bergaust L, Bakken LR, Rowley G, Kjos M, Shapleigh JP, Frostegård Å.   +8 more
europepmc   +1 more source