Results 91 to 100 of about 271,410 (338)

Increase in the biomass of some green algae species in nitrate and ammonium mediums depending on auto-, mixo- or heterotrophic conditions

open access: yesActa Societatis Botanicorum Poloniae, 2014
The increase in total dry mass and protein in cultures of Chlorella pyrenoidosa, Scenedesmus quadricauda and Ankistrodesmus acicularis was studied. Under autotrophic conditions, increases in dry mass were, as a rule, larger in the nitrate medium than in ...
Stefan Gumiński   +2 more
doaj   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Nitrification amplifies the decreasing trends of atmospheric oxygen and implies a larger land carbon uptake [PDF]

open access: yes, 2007
[1] Atmospheric O-2 trend measurements are used to partition global oceanic and land biotic carbon sinks on a multiannual basis. The underlying principle is that a terrestrial uptake or release of CO2 is accompanied by an opposite flux of O-2.
Bopp, L   +4 more
core   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Manure Incorporation and Reduced Tillage Corn Trial [PDF]

open access: yes, 2015
Timely manure incorporation can reduce nutrient losses to the atmosphere and surface runoff. Keeping valuable nutrients, like nitrogen, in the soil can help reduce the purchase of expensive commercial fertilizers.
Calderwood, Lily   +6 more
core   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Boosting nutritional quality of Urtica dioica L. to resist climate change

open access: yesFrontiers in Plant Science
IntroductionMore than ever, traditional agricultural practices need a shift towards more resilient, sustainable, modern and adaptable practices that benefit the health of the planet and people.
Nevena Opačić   +9 more
doaj   +1 more source

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