Results 91 to 100 of about 555,047 (351)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Aminoethyl nitrate – the novel super nitrate? [PDF]

British Journal of Pharmacology, 2009
Long‐term use of most organic nitrates is limited by development of tolerance, induction of oxidative stress and endothelial dysfunction. In this issue of the BJP, Schuhmacher et al. characterized a novel class of organic nitrates with amino moieties (aminoalkyl nitrates).
openaire   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Impact du chargement d'arrière-saison sur les teneurs en azote potentiellement lessivable en prairie : références établies dans le sud-est de la Belgique

Biotechnologie, Agronomie, Société et Environnement, 2013
Impact of cattle stocking rate, under grazing, during autumn on potential nitrogen leaching: reference values established in the south-east of Belgium.
Hennart, S., Lambert, A., Stilmant, D.
doaj  

Nitrates in the treatment of patients with coronary artery disease. The role of aerosol formulations

Медицинский совет, 2014
Nitrates have been commonly used in the treatment of patients with cardiovascular disease (CVD) for about 150 years. However, the feasibility and safety of nitrates in cardiology remains a matter of debate till today. Among CVDs, coronary artery disease (
AG Evdokimova, VV Evdokimov, NA Kozhina
doaj   +1 more source

Oilseed Meal as a Fertility Amendment in Sweet Corn [PDF]

, 2013
Many Northeast growers are integrating oilseed crops such as canola, soybeans, and sunflower into their operation, in hopes of on-farm fuel production, value-added products, and/or livestock feed.
Burke, Conner, Cummings, Erica, Darby, Heather, Harwood, Hannah Harwood, Monahan, Susan   +4 more
core   +1 more source

Isoprene photooxidation: new insights into the production of acids and organic nitrates

, 2009
. We describe a nearly explicit chemical mechanism for isoprene photooxidation guided by chamber studies that include time-resolved observation of an extensive suite of volatile compounds.
F. Paulot, J. Crounse, H. Kjaergaard, J. Kroll, J. Seinfeld, P. Wennberg   +5 more
semanticscholar   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Response of Chinese cabbage grown in the spring season to differentiated forms of nitrogen fertilisation

Folia Horticulturae, 2011
In the experiment carried out in the Experimental Station belonging to the Wrocław University of Environmental and Life Sciences in 2004-2006, we estimated the effect of the type of the nitrogen fertiliser (ammonium nitrate, calcium nitrate, ammonium ...
Krężel Jan, Kołota Eugeniusz
doaj   +1 more source

Pain in angina attack

Медицинский совет, 2014
For many years, coronary heart disease (CHD) has been the main cause of death in many developed countries. At present, cardiovascular diseases (CVD) play a crucial role in the evolution of total mortality in Russia.
MV Kuznetsova
doaj   +1 more source