Results 141 to 150 of about 555,047 (351)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Revisiting nitrates use in pre-shock state of contemporary cardiogenic shock classification

Frontiers in Cardiovascular Medicine
Patients at each shock stage may behave and present differently with a spectrum of shock severity and adverse outcomes. Shock severity, shock aetiology, and several factors should be integrated in management decision-making.
Rasha Kaddoura, Ashfaq Patel, Abdul Rahman Arabi   +2 more
doaj   +1 more source

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Marginal abatement costs for reducing leaching of nitrates in Croatian agriculture [PDF]

, 2005
The aim of this paper is to estimate marginal abatement costs (MAC) of N-fertiliser tax policies which aim to prevent NO3 levels from rising. Estimates of MAC provide information on how large reductions in Nfertilisation rates should be before other ...
Franic, Ramona, Grgic, Zoran, Kisic, Ivica, Mesic, Milan, Sumelius, John   +4 more
core  

Nitrate signalling: Calcium bridges the nitrate gap

Nature Plants, 2017
Nitrate signalling: Calcium bridges the nitrate gap.
openaire   +4 more sources

Temporal Trends and Short‐ and Long‐Term Mortality of People With Acute Myocardial Infarction and Rheumatoid Arthritis: A Nationwide Cohort Study

Arthritis Care &Research, EarlyView.
Objective We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analyzed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalized with AMI between 2005 and 2019 from the Myocardial Ischaemia ...
Megan Butler, Nicholas Weight, Muhammad Rashid, Rodrigo Bagur, Purvi Parwani, Samantha Hider, Edward Roddy, Robert Butler, Mamas A. Mamas   +8 more
wiley   +1 more source

Ubiquity of organic nitrates from nighttime chemistry in the European submicron aerosol

, 2016
A. Kiendler‐Scharr, A. Mensah, E. Friese, D. Topping, E. Nemitz, A. Prévôt, M. Äijälä, J. Allan, F. Canonaco, M. Canagaratna, S. Carbone, M. Crippa, M. Osto, D. Day, P. D. Carlo, C. Marco, H. Elbern, A. Eriksson, E. Freney, L. Hao, H. Herrmann, L. Hildebrandt, R. Hillamo, J. Jimenez, A. Laaksonen, G. Mcfiggans, C. Mohr, C. O’Dowd, R. Otjes, J. Ovadnevaitė, S. Pandis, L. Poulain, P. Schlag, K. Sellegri, E. Swietlicki, P. Tiitta, A. Vermeulen, A. Wahner, D. Worsnop, H. C. Wu   +39 more
semanticscholar   +2 more sources

Multilevel governance patterns and the protection of groundwater and drinking water in Florida and the Netherlands [PDF]

, 2000
This paper develops a model of ‘governance’ as an aid for comparing such\ud governance structures and applies these to a particular policy arena: policies\ud on the protection of groundwater and on drinking water quality in the\ud Netherlands and Florida.
Bressers, J.T.A., Kuks, S.M.M.
core   +1 more source

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

Arthritis Care &Research, EarlyView.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown   +4 more
wiley   +1 more source