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Clinical Pharmacokinetics of Nitrazepam
Clinical Pharmacokinetics, 1981Nitrazepam is one of the oldest benzodiazepines and is widely used as an hypnotic throughout the world, except North America, where it is not available. It is a safe hypnotic, with low acute toxicity and minor side effects. Development of tolerance or dependence and withdrawal symptoms are rare and very few known interactions with other drugs exist ...
L, Kangas, D D, Breimer
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Nitrazepam (Mogadon) Dependence
British Journal of Psychiatry, 1975Evidences suggest that the predisposed individual can develop dependence to various tranquillizers even to the extent of physical dependence similar to that seen with the barbiturates. Dependence can develop to benzodiazepine derivatives, and cases have been reported mainly for chlordiazepoxide, diazepam and oxazepam.
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Spectrophotometric determination of chlordiazepoxide and nitrazepam
Talanta, 1988The use of ethyl acetoacetate in the spectrophotometric determination of chlordiazepoxide and nitrazepam has been investigated. The procedure is based on coupling the diazotized drugs with ethyl acetoacetate, which possesses an active methylene group. The products have absorption maxima at 408 and 482 nm and apparent molar absorptivities of 2.74 x 10(4)
M I, Walash, M, Rizk, A, El-Brashy
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Determination of nitrazepam in poisoning cases
Forensic Science, 1974Abstract This paper presents a technique for the separation, identification and measurement of nitrazepam in biological materials. The method has been applied to two cases of fatal ingestion of nitrazepam.
J S, Oliver, H, Smith
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