Results 91 to 100 of about 3,430,031 (362)

Novel Drug‐Testing Platform for Vascular Injury‐induced Intimal Hyperplasia Using a Microphysiological System

open access: yesAdvanced Healthcare Materials, EarlyView.
This study develops a 3D vascular injury model using a microphysiological system that mimics key features of intimal hyperplasia. Antiproliferative drugs reduced VSMC proliferation but worsened endothelialdenudation. A combination of diphenyleneiodonium and quercetin effectively reduced proliferation and migration of VSMC and inflammation while ...
Ungsig Nam   +7 more
wiley   +1 more source

Role of Nitric Oxide in Neuronal Damages in Critical Conditions

open access: yesОбщая реаниматология, 2009
The presented review of literature covers the current notions of the role of nitric oxide and its metabolism in the development of encephalopathies in critically ill patients.
A. V. Kiseleva   +2 more
doaj   +1 more source

Synthetic Antiferromagnetic Designer Nanodisks for High‐Performance Magnetic Separation

open access: yesAdvanced Healthcare Materials, EarlyView.
Micromagnetic‐modeling‐based design and scalable fabrication of synthetic antiferromagnet (SAF) magnetic disk particles (MDPs) using sputter deposition enable high‐performance magnetic separation. The SAF MDPs achieve high colloidal stability and magnetic responsiveness and enable efficient magnetic separation, outperforming conventional particles ...
Subas Scheibler   +14 more
wiley   +1 more source

Plant H2S and Transcription Factors (TFs) Interactions: Unexplored Area

open access: yesFrontiers in Bioscience-Landmark
Plant hydrogen sulfide (H2S) metabolism has garnered noteworthy attention due to its role in regulating many plant processes. The primary mechanism by which H2S exerts its signaling functions is through its reversible interaction with thiol groups on ...
Francisco J Corpas
doaj   +1 more source

Conditioned Media from Mechanically Stimulated Macrophages Upregulate Osteogenic Genes in Human Mesenchymal Stromal Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex   +4 more
wiley   +1 more source

Nitric oxide as a mediator of inflammation?—You had better believe it

open access: yesMediators of Inflammation, 1995
Nitric oxide has enigmatic qualities in inflammation. In order to appreciate the precise contributions of nitric oxide to a pathophysiological process, one must account for enzyme source, coproduction of oxidants and antioxidant defences, time, rate of ...
Mark J. S. Miller, Matthew B. Grisham
doaj   +1 more source

Oh no, not nitric oxide!

open access: yesThe Central African journal of medicine, 1999
Nitric oxide (NO) is a unique, endogenous regulatory molecule that is involved in a wide variety of physiological processes in multiple organ systems. This simple gas functions as a cellular messenger in a broad range of biological activities that include blood pressure regulation, immunomodulation and neurotransmission.
openaire   +4 more sources

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