Results 271 to 280 of about 848,340 (316)
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Nitric Oxide and Atherosclerosis
Nitric Oxide, 2001Endothelial dysfunction has been shown in a wide range of vascular disorders including atherosclerosis and related diseases. Here, we examine and address the complex relationship among nitric oxide (NO)-mediated pathways and atherogenesis. In view of the numerous pathophysiological actions of NO, abnormalities could potentially occur at many sites: (a)
NAPOLI, Claudio, IGNARRO LJ
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Journal of Neuro-Oncology, 2000
The steps required for new vessel growth are biologically complex and require coordinate regulation of contributing components, including modifications of cell--cell interactions, proliferation and migration of endothelial cells and matrix degradation.
Ziche, Marina, Morbidelli, Lucia
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The steps required for new vessel growth are biologically complex and require coordinate regulation of contributing components, including modifications of cell--cell interactions, proliferation and migration of endothelial cells and matrix degradation.
Ziche, Marina, Morbidelli, Lucia
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Respiratory Care Clinics, 2002
Inhaled NO offers a novel therapy for the treatment of pulmonary hypertensive diseases and the symptomatic relief of hypoxemia. The use of iNO reduces the necessity for ECMO in newborns and infants with acute hypoxemic respiratory failure. Proper indications, contraindications, dosing criteria, and implications of the toxic actions of NO must be ...
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Inhaled NO offers a novel therapy for the treatment of pulmonary hypertensive diseases and the symptomatic relief of hypoxemia. The use of iNO reduces the necessity for ECMO in newborns and infants with acute hypoxemic respiratory failure. Proper indications, contraindications, dosing criteria, and implications of the toxic actions of NO must be ...
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Nitric oxide, nitric oxide synthase, and hypertensive vascular disease
Current Hypertension Reports, 1999In normotension the endothelium produces mainly nitric oxide (NO) and prostacyclin, and the vasodilator and growth inhibitory influence predominates. Hypertension, however, is associated with a shift towards enhanced constriction and vascular hypertrophy.
R, Busse, I, Fleming
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1996
Sepsis or the septic syndrome is the number one cause of mortality in todays intensive care. Overall mortality of sepsis is estimated to be 40 to 60% and when shock or organ failure is present mortality rate is even higher despite recent progress in antibiotic and vasopressor therapy (Bone et al. 1991).
Avontuur, J, Bruining, HA, Ince, Can
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Sepsis or the septic syndrome is the number one cause of mortality in todays intensive care. Overall mortality of sepsis is estimated to be 40 to 60% and when shock or organ failure is present mortality rate is even higher despite recent progress in antibiotic and vasopressor therapy (Bone et al. 1991).
Avontuur, J, Bruining, HA, Ince, Can
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Multimodality imaging of nitric oxide and nitric oxide synthases
Free Radical Biology and Medicine, 2009Nitric oxide (NO) and NO synthases (NOSs) are crucial factors in many pathophysiological processes such as inflammation, vascular/neurological function, and many types of cancer. Noninvasive imaging of NO or NOS can provide new insights in understanding these diseases and facilitate the development of novel therapeutic strategies.
Hao, Hong, Jiangtao, Sun, Weibo, Cai
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Pulmonary hypertension, nitric oxide and nitric oxide-releasing compounds
Expert Review of Respiratory Medicine, 2011Nitric oxide (NO) is an important molecule in the mammalian cardiovascular system and the elucidation of its biological role has led to the awarding of a Nobel prize in medicine. There have been many significant discoveries in NO biology over the past two decades and translation of these developments from bench to bedside has allowed an explosion of ...
Guy, Hagan, Joanna, Pepke-Zaba
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Nitric oxide and nitric oxide synthase activity in plants
Phytochemistry, 2004Research on NO in plants has gained considerable attention in recent years mainly due to its function in plant growth and development and as a key signalling molecule in different intracellular processes in plants. The NO emission from plants is known since the 1970s, and now there is abundant information on the multiple effects of exogenously applied ...
Luis A, del Río +2 more
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Oxidized lipoproteins and nitric oxide
Current Opinion in Lipidology, 1996Nitric oxide has an important biological role as endothelium-derived relaxing factor, a key agent in the maintenance of normal vascular tone. It can also suppress lipoprotein oxidation, a potential anti-atherogenic property. However, in arteries subject to hypercholesterolemia or atherosclerosis, whereas nitric oxide synthesis is normal its biological ...
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