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Nitric oxide

The International Journal of Biochemistry & Cell Biology, 1997
Nitric oxide (NO) is a gas with diverse biological activities produced from arginine by NO synthases. It is capable of interacting with a number of molecules, most notably superoxide, forming peroxynitrite, which, in turn, can mediate bactericidal or cytotoxic reactions.
R A, Robbins, M B, Grisham
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Nitric Oxide and Angiogenesis

Journal of Neuro-Oncology, 2000
The steps required for new vessel growth are biologically complex and require coordinate regulation of contributing components, including modifications of cell--cell interactions, proliferation and migration of endothelial cells and matrix degradation.
Ziche, Marina, Morbidelli, Lucia
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Exhaled Nitric Oxide

Immunology and Allergy Clinics of North America, 2007
Nitric oxide (NO) is now considered an important biomarker for respiratory disease. Studies have confirmed that the fractional concentration of exhaled nitric oxide (FENO) is elevated in the airways of patients who have asthma in comparison with controls.
Lora Stewart, Rohit K. Katial
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Nitric Oxide in the Airways

The Journal of Allergy and Clinical Immunology: In Practice, 2007
This review briefly explains the basic facts about nitric oxide, which is entering clinical practice as a measure of lower airways inflammation and is likely also to be employed in otorhinolaryngological practice.These include the validity of nasal nitric oxide in diagnosing primary ciliary dyskinesia and in monitoring the response to chronic ...
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Nitric Oxide and Atherosclerosis

Nitric Oxide, 2001
Endothelial dysfunction has been shown in a wide range of vascular disorders including atherosclerosis and related diseases. Here, we examine and address the complex relationship among nitric oxide (NO)-mediated pathways and atherogenesis. In view of the numerous pathophysiological actions of NO, abnormalities could potentially occur at many sites: (a)
NAPOLI, Claudio, IGNARRO LJ
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Nitric oxide

European Journal of Pediatrics, 1994
Although persistent pulmonary hypertension of the newborn (PPHN) has been considered to be a relatively rare condition, there is increasing evidence that pulmonary vasoconstriction is a common finding in moderate and severe respiratory distress syndrome.
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Sepsis and Nitric Oxide

1996
Sepsis or the septic syndrome is the number one cause of mortality in todays intensive care. Overall mortality of sepsis is estimated to be 40 to 60% and when shock or organ failure is present mortality rate is even higher despite recent progress in antibiotic and vasopressor therapy (Bone et al. 1991).
Can Ince   +2 more
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Nitric Oxide and Inflammation

Inflammation & Allergy-Drug Targets, 2006
There are several pre-clinical studies on the involvement of NO in inflammation. From this large amount of information it is clear that virtually every cell and many immunological parameters are modulated by NO. Thus, the final outcome is that NO cannot be rigidly classified as an anti-inflammatory or pro-inflammatory molecule.
CIRINO, GIUSEPPE   +2 more
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Nitric oxide in invertebrates

Molecular Neurobiology, 1998
Nitric oxide (NO) is considered an important signaling molecule implied in different physiological processes, including nervous transmission, vascular regulation, immune defense, and in the pathogenesis of several diseases. The presence of NO is well demonstrated in all vertebrates.
COLASANTI, Marco, VENTURINI G.
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Melatonin and nitric oxide

Journal of Endocrinological Investigation, 2006
Melatonin is a product of the amino acid tryptophan in the pineal gland. Once synthesized, the specific mechanisms governing the release of melatonin from the pineal gland and its functions are largely unknown. Besides its regulatory role in circadian rhythms in mammals, because of its widespread subcellular distribution, melatonin contributes to the ...
Goktas, Altan   +2 more
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