Results 201 to 210 of about 200,814 (309)

Inflammation-Induced Nitric Oxide Synthase May Mediate the Acute Hypotensive Effect of ST36 Stimulation. [PDF]

J Inflamm Res
Lei QL, Yue X, Sun XX, Zhu LJ, Liu S, Hong H, Tang Z, Cao X.   +7 more
europepmc   +1 more source

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

Ibrain, EarlyView.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard, Vivian Kapio Abem, Sagor Kumar Roy   +2 more
wiley   +1 more source

Evaluation of Plasma Nitric Oxide and Serum Endothelial Nitric Oxide Synthase in Pulmonary Hypertensive Dogs: A Clinical and Echocardiography Investigation. [PDF]

Vet Sci
Rattanakanokchai S, Fungbun N, Senaphan K, Jitpean S, Ployngam T.   +4 more
europepmc   +1 more source

Nano‐plastics disrupt systemic metabolism by remodeling the bile acid–microbiota axis and driving hepatic–intestinal dysfunction

iMeta, EarlyView.
The pervasiveness of microplastic pollution poses a growing health risk, yet its long‐term metabolic consequences remain poorly defined. Here, we exposed mice to polyethylene terephthalate nanoparticle (NP) and combined histopathology, biochemistry, metabolomics, and metagenomics to resolve their interactions.
Yi Zhang, Zheng Lin, Runtong Huang, Yang Zhang, Lei Wang, Zan Fu, Chao Wang, Shuai Xiao, Heru Pramono, Kui Xu, Zhimin Xu, Yulong Yin   +11 more
wiley   +1 more source

Development of a human colorectal carcinoma cell-based platform for studying inducible nitric oxide synthase expression and nitric oxide signaling dynamics. [PDF]

Front Mol Biosci
Chen X, Grimm EA, Qin Y.
europepmc   +1 more source

Neuronal and Endothelial Nitric Oxide Synthases in the Paraventricular Nucleus Modulate Sympathetic Overdrive in Insulin-Resistant Rats

, 2015
Qing-Bo Lu, Xue-mei Feng, Ning Tong, Hai‐Jian Sun, Lei Ding, Yujiao Wang, Xuan Wang, Ye‐Bo Zhou   +7 more
openalex   +2 more sources

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

Interdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui, Jie Gao, Tianchang Tao, Peng Wang, Zhihao Huang, Yuyang She, Jiajie Li, Jingwan Su, Zhe Lu, Jianchao Qiao, Song Wang, Xiaodong Sun, Mohan Li   +12 more
wiley   +1 more source

A Refined Carbohydrate-Rich Diet Reduces Vascular Reactivity Through Endothelial Oxidative Stress and Increased Nitric Oxide: The Involvement of Inducible Nitric Oxide Synthase. [PDF]

Nutrients
Neumann K, Mawandji NBS, Schereider IRG, de Oliveira EC, Vieira JM, Bolsoni-Lopes A, Graceli JB, Dantas JA, Cardoso LS, Vassallo DV, Nunes KZ.   +10 more
europepmc   +1 more source

Adipose‐derived small extracellular vesicles exacerbate microvascular dysfunction in heart failure with preserved ejection fraction via mmu‐miR‐582‐3p‐mediated Rap1b suppression

Interdisciplinary Medicine, EarlyView.
This study reveals that small extracellular vesicles (sEVs) from visceral fat compromise coronary microcirculation in a mouse model of heart failure with preserved ejection fraction (HFpEF). The SGLT2 inhibitor canagliflozin emerges as a therapeutic strategy, improving cardiac function and endothelial health.
Lu Chen, Qiuhan Wang, Mengjia Shen, Mingjue Li, Yingqi Zhu, Cankun Zheng, Siyuan Ma, Hairuo Lin, Xiaokang Fu, Rui Zhang, Jianping Bin, Yulin Liao, Qiancheng Wang   +12 more
wiley   +1 more source

Advances in the Regulation of Inflammatory Mediators in Nitric Oxide Synthase: Implications for Disease Modulation and Therapeutic Approaches. [PDF]

Int J Mol Sci
Kim ME, Lee JS.
europepmc   +1 more source