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Modulation of nitric oxide synthase by nitric oxide donor compounds in migraine
International Journal of Clinical & Laboratory Research, 1998A controlled study was performed to assess the involvement of the nitric oxide pathway in migraine pathophysiology. Thirteen patients with migraine without aura and seven clinically healthy subjects (C) were selected. All of the migraine patients were studied both before, during an asymptomatic phase (t0), and 1 h after the administration of 5 mg ...
MARTELLETTI, Paolo+5 more
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Tetrahydrobiopterin and Nitric Oxide Synthase Recouplers
2020Generation of nitric oxide (NO) by the nitric oxide synthase (NOS) enzymes plays multiple signalling roles in every organ system, with crucial roles in the cardiovascular system, mediated by endothelial nitric oxide synthase (eNOS, encoded by NOS3) and neuronal nitric oxide synthase (nNOS, encoded by NOS1) in regulation of blood pressure, flow, oxygen ...
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Immunobiology of Nitric Oxide and Regulation of Inducible Nitric Oxide Synthase
2017Nitric oxide (NO) is a bioactive gas that has multiple roles in innate and adaptive immune responses. In macrophages, nitric oxide is produced by inducible nitric oxide synthase upon microbial and cytokine stimulation. It is needed for host defense against pathogens and for immune regulation.
Martin Lee+4 more
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Nitric Oxide Synthase Isoforms and Nitric Oxide Biosynthesis
1997The L-arginine/nitric oxide (NO•) pathway is now recognized as a key physiological and pathophysiological mediator of many biological processes including vascular, neurologic and immune function (Nathan 1992; Feldman et al. 1993a; Bredt and Snyder 1994).
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Rapid growth of new atmospheric particles by nitric acid and ammonia condensation
Nature, 2020Marcel Zauner-wieczorek+2 more
exaly
Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease
Nature Medicine, 2002Irfan Khan, Neil Hogg, Mark T Gladwin
exaly +2 more sources