Results 221 to 230 of about 437,208 (310)

Therapeutic Challenges of Diabetes Mellitus-Related Erectile Dysfunction and The Potential Therapeutic Role of Medicinal Plants: A Narrative Review. [PDF]

Drug Des Devel Ther
Wang H, Chang H, Sun D, Wang A, Yan B, Chung E.   +5 more
europepmc   +1 more source

Advances in the Study of Pluripotent Stem Cells in Livestock

Cell Proliferation, EarlyView.
Livestock pluripotent stem cells include embryonic stem cells (ESCs) isolated from the inner cell mass of blastocysts and induced pluripotent stem cells (iPSCs) derived from somatic cell reprogramming. They hold significant potential for applications in livestock breed improvement, rapid propagation, human disease modelling and human organ ...
Xinyi Zhou, Chen Gao, Wenxuan Zhao, Xinhua Wei, Dawei Yu, Huiying Zou, Weihua Du   +6 more
wiley   +1 more source

N-actylcysteine inhibits diethyl phthalate-induced inflammation via JNK and STAT pathway in RAW264.7 macrophages. [PDF]

BMC Mol Cell Biol
Kim JH, Lee JH, Koo YJ, Song JW.
europepmc   +1 more source

The impact of immature granulocytes on the outcome of patients with decompensated cirrhosis

European Journal of Clinical Investigation, EarlyView.
Immature granulocyte (IG) count and percentage had a predictive role in patients with decompensated cirrhosis, making them an objective and easily available marker of prognosis for this group of patients. In addition, IG percentage was the only factor independently associated with transplant‐free survival.
Magdalini Adamantou, Dimitrios Glaros, Evangelinos Michelis, Apostolos Papageorgiou, Eleni Adamopoulou, Antonia Alevizou, Menelaos Athanasiadis, Eleni Pergantina, Vasiliki E. Georgakopoulou, Vasileios Lekakis, Evangelos Cholongitas   +10 more
wiley   +1 more source

Antioxidant, Antidiabetic, and Vasorelaxant Effects of Ethanolic Extract from the Seeds of <i>Swietenia humilis</i>. [PDF]

Int J Mol Sci
Hernández EAG, Galindo GC, Chávez RSM, Moreno PC, Barajas MI, Duque TEV, Antúnez APH, Mondragón LDV, Guerrero GAM, Cobos DS.   +9 more
europepmc   +1 more source

Blocking the innate immune CD1d/NKT cell axis prevents the development of cortical hyperexcitability and posttraumatic epilepsy

Epilepsia, EarlyView.
Abstract Objective Posttraumatic epilepsy (PTE) that develops after a traumatic brain injury (TBI) cannot be prevented by current treatments. Although neuroinflammation is involved in epileptogenesis, a potential role for cellular immunity in this process is largely unknown.
Xingjie Ping, Wenhui Xiong, Raj Priya, Jianyun Liu, Season K. Wyatt‐Johnson, Randy R. Brutkiewicz, Xiaoming Jin   +6 more
wiley   +1 more source

Hypoxia Combined With Interleukin-17 Regulates Hypoxia-Inducible Factor-1α/Endothelial Nitric Oxide Synthase Expression in Pulmonary Artery Endothelial Cells. [PDF]

J Cell Mol Med
Sun S, Mao J, Ding Y, Liu L, Gong J, Yang S, Li J, Kuang T, Miao R, Yang Y.   +9 more
europepmc   +1 more source

Macrophages and autophagy: partners in crime

The FEBS Journal, EarlyView.
Autophagy is a key regulator of macrophage function, influencing critical processes like polarization, cytokine secretion, and phagocytosis. Its impact on macrophage behavior varies across different tissues and disease contexts, where it can either promote protective responses or contribute to detrimental outcomes, depending on the physiological or ...
Alessandra Vitaliti, Alessio Reggio, Alessandro Palma   +2 more
wiley   +1 more source

The role of glucagon-like peptide-1 receptor (GLP-1R) agonists in enhancing endothelial function: a potential avenue for improving heart failure with preserved ejection fraction (HFpEF). [PDF]

Cardiovasc Diabetol
Hullon D, Subeh GK, Volkova Y, Janiec K, Trach A, Mnevets R.   +5 more
europepmc   +1 more source

Fatty‐acid amide hydrolase inhibition mitigates Alzheimer's disease progression in mouse models of amyloidosis

The FEBS Journal, EarlyView.
Enhancing endocannabinoid signaling by targeting FAAH effectively mitigates cognitive deficits, reduces amyloid pathology, and modulates neuroinflammatory responses in a preclinical model of Alzheimer's disease. This effect is potentially mediated by attenuating the Aβ‐induced overexpression of the Bace1 gene through CB1‐dependent hypermethylation of ...
Sergio Oddi, Lucia Scipioni, Antonio Totaro, Giacomo Giacovazzo, Francesca Ciaramellano, Daniel Tortolani, Alessandro Leuti, Rita Businaro, Federica Armeli, Andras Bilkei‐Gorzo, Roberto Coccurello, Andreas Zimmer, Mauro Maccarrone   +12 more
wiley   +1 more source