Results 151 to 160 of about 63,869 (332)

Amphiregulin and Epiregulin Confer Radioresistance in Esophageal Squamous Cell Carcinoma Through Oxidative Phosphorylation

Advanced Science, EarlyView.
Oxidative phosphorylation (OXPHOS) activity serves as a critical metabolic determinant of radiotherapy outcomes in esophageal squamous cell carcinoma (ESCC). The CEBPB/AREG/EREG axis drives radioresistance in ESCC by reprogramming OXPHOS. AREG and EREG function as predictive biomarkers for nCRT response and prognosis of ESCC patients.
Zhang Lin, Meilian Yao, Xin Xu, Dong Zhang, Lei Xu, Ling Rong, Xiaohang Wang, Yi Duan, Chengkun Chen, Jun Gu, Yao Zhang, Qiang Liu, Qing Ye, Gaoping Cui, Yujun Hao, Xiumei Ma   +15 more
wiley   +1 more source

Cassini: Mission to Saturn and Titan [PDF]

The Cassini Mission to Saturn and Titan represents an important step into the exploration of the outerplanets. It will expand on the flyby encounters of Pioneer and Voyager and parallel the detailed exploration of the Jupiter system to be accomplished by
Flury, Walter, Horn, Linda J., Kerridge, Stuart J., Lebreton, Jean-Pierre, Stetson, Douglas S., Stoller, Richard L., Tan, Grace H.   +6 more
core   +1 more source

Mitochondrial CISD1 Modulates Microglial Metabolic Reprogramming to Drive Stress Susceptibility in Mice

Advanced Science, EarlyView.
CDGSH iron sulfur domain 1 (CISD1) mitigates oxidative stress by promoting NADH oxidation and Coenzyme Q (CoQ) reduction. Under chronic stress, elevated CISD1 expression in microglia enhances NAD⁺ production, thereby increasing GAPDH activity and glycolytic flux, while reducing ATP synthesis by inhibiting proton transfer from mitochondrial complexes I ...
Wanting Dong, Duo Liu, Songsen Fu, Jiaming Zhang, Xi Chen, Songqiang Huang   +5 more
wiley   +1 more source

Everything you ever wanted to know about primary amines, secondary amines, tertiary amines, diamines. Quaternary ammonium chlorides, amine acetates, nitriles, amides, ethoxylated amines, amine oxides, specialty chemicals, fatty acid esters and fatty acids. [PDF]

, 1979

openalex   +1 more source

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

Advanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou, Junxian Chen, Hongxia Zhang, Lu Guo, Kevin Mai, Elijah Abraham, Dilip V. Prajapati, Yue Chang, Jing Ning, Xinchen Wang, Defeng Li, Dan‐Dan Zhang, Jianghua Sun, Rebecca A. Butcher, Lilin Zhao   +14 more
wiley   +1 more source

Nitriles as main products from the oxidation of primary amines by ferrate(VI): Kinetics, mechanisms and toxicological implications for nitrogenous disinfection byproduct control

, 2021
Valentin Rougé, Jaedon Shin, Pham Thi Thai Ha Nguyen, Dongwoo Jang, Woongbae Lee, Beate I. Escher, Yunho Lee   +6 more
openalex   +2 more sources

Automated Benchmarking of Variable‐Property Soft Robotic Fingertips to Enable Task‐Optimized Sensor Selection

Advanced Science, EarlyView.
Sensorized fingertips are needed to unlock robotic dexterity, versatility, and diverse interactions. Here, 15 identically‐shaped robotic fingertips are benchmarked by a fully automated toolchange system, covering eight different materials and six broadly‐ranging sensing mechanisms.
David Hardman, Benhui Dai, Qinghua Guan, Antonia Georgopoulou, Fumiya Iida, Josie Hughes   +5 more
wiley   +1 more source

Investigating Mitochondrial Viscosity in Ferroptosis‐Mediated Drug‐Induced Liver Injury using a Double‐Targeted Strategy

Advanced Science, EarlyView.
Utilizing a mitochondrial double‐targeted strategy, a novel near‐infrared fluorescent probe (FTZ‐2) is established for monitoring viscosity variations in ferroptosis‐mediated drug‐induced liver injury. In summary, this work provided a practical strategy for the early diagnosis and evaluation of liver injury.
Yongqing Zhou, Yan Wang, Bing Huang, Hosoowi Lee, Mei Yan, Juyoung Yoon   +5 more
wiley   +1 more source

When We Suggested Hydrogen Cyanide To Synthesize A Special Nitrile, You Should Have Seen Their Reaction. [PDF]

, 1991

openalex   +1 more source

Heavy Prussian Blue Analog with Magnetic Ordering above 400 K

Advanced Science, EarlyView.
A cyanido‐bridged vanadium(II)–hexacyanomolybdate(III) Prussian Blue analog synthesized mechanochemically exhibits ferrimagnetic ordering above 400 K. SQUID magnetometry and XMCD experiments confirm antiparallel alignment of V and Mo moments. This establishes hexacyanomolybdate(III) as a robust precursor for high‐temperature molecule‐based magnets ...
Michał Magott, Gabriela Handzlik, Dominik Dzierżek, Alexey Maximenko, Itziar Oyarzabal, Nathan J. Yutronkie, Fabrice Wilhelm, Andrei Rogalev, Dawid Pinkowicz   +8 more
wiley   +1 more source