Results 221 to 230 of about 202,861 (363)

Design and Synthesis of Tetrahydropyrrolo[3,4‐c]Pyrazole Sigma‐1 Receptor Ligands

open access: yesChemMedChem, EarlyView.
This study highlights the tetrahydropyrrolo[3,4‐c]pyrazole scaffold as a promising platform for S1R ligands development. Key findings include compound 19’s high S1R affinity (Ki=75 nM), influenced by strategic nitrogen substitutions and reduced steric hindrance.
Giuseppe Cosentino   +7 more
wiley   +1 more source

Potential issues specific to cytotoxicity tests of cellulose nanofibrils

open access: yesJournal of Applied Toxicology, Volume 43, Issue 1, Page 195-207, January 2023., 2023
Abstract Cellulose nanofibrils (also called cellulose nanofibers or nanofibrillated cellulose [CNFs]) are novel polymers derived from biomass with excellent physicochemical properties and various potential applications. However, the introduction of such new materials into the market requires thorough safety studies to be conducted.
Akihiro Moriyama   +2 more
wiley   +1 more source

From In Situ Monitoring to Better Understanding of the Suzuki‐Miyaura Cross Coupling in the Solid State

open access: yesChemistry–Methods, EarlyView.
Effects of Additives, Base, Catalyst, and substrate (ABCs) on the mechanochemically‐induced Suzuki‐Miyaura cross coupling have been studied comparing the time‐resolved product formation obtained by in situ Raman monitoring of the reactions. Abstract Effects of various Additives, Base, Catalyst, as well as substrates on the mechanochemically‐induced ...
Mario Pajić   +4 more
wiley   +1 more source

Extremophilic nitrite-oxidizing Chloroflexi from Yellowstone hot springs

open access: yesThe ISME Journal, 2019
E. Spieck   +9 more
semanticscholar   +1 more source

Diazonium Salts in Visible Light Photocatalysis – a Focused Overview of their Application in Continuous Flow Synthesis

open access: yesChemPhotoChem, EarlyView.
The combination of continuous flow technology and visible light photocatalysis has been used to improve the safety and productivity of reactions with diazonium salts as reactive intermediates. This approach has proven to be a reliable method for various organic synthesis routes with diazonium salts under mild and well‐defined conditions.
Christoph Deckers, Thomas H. Rehm
wiley   +1 more source

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