Design and Synthesis of Tetrahydropyrrolo[3,4‐c]Pyrazole Sigma‐1 Receptor Ligands
This study highlights the tetrahydropyrrolo[3,4‐c]pyrazole scaffold as a promising platform for S1R ligands development. Key findings include compound 19’s high S1R affinity (Ki=75 nM), influenced by strategic nitrogen substitutions and reduced steric hindrance.
Giuseppe Cosentino+7 more
wiley +1 more source
Potential issues specific to cytotoxicity tests of cellulose nanofibrils
Abstract Cellulose nanofibrils (also called cellulose nanofibers or nanofibrillated cellulose [CNFs]) are novel polymers derived from biomass with excellent physicochemical properties and various potential applications. However, the introduction of such new materials into the market requires thorough safety studies to be conducted.
Akihiro Moriyama+2 more
wiley +1 more source
Impact of Organic and Conventional Vegetable-Based Curing Ingredients on Frankfurter Quality and Sensory Attributes. [PDF]
Sheng S, Ricke SC, Silva EM, Claus JR.
europepmc +1 more source
Slit-Lamp Study of the Aqueous Veins in Simple Glaucoma during the Amyl Nitrite Test [PDF]
G Cristini, N. Pagliarani
openalex +1 more source
Effects of Additives, Base, Catalyst, and substrate (ABCs) on the mechanochemically‐induced Suzuki‐Miyaura cross coupling have been studied comparing the time‐resolved product formation obtained by in situ Raman monitoring of the reactions. Abstract Effects of various Additives, Base, Catalyst, as well as substrates on the mechanochemically‐induced ...
Mario Pajić+4 more
wiley +1 more source
Ultrasound-assisted one-pot cloud point extraction for spectrophotometric nitrate and nitrite determination in sausage products using <i>Careya arborea</i> Roxb. leaf extracts. [PDF]
Supharoek SA+5 more
europepmc +1 more source
Extremophilic nitrite-oxidizing Chloroflexi from Yellowstone hot springs
E. Spieck+9 more
semanticscholar +1 more source
Recherches spectroscopiques sur les esters de l'acide nitreux. Le spectre infra‐rouge du nitrite de méthyle monodeutéré [PDF]
P. Tarte
openalex +1 more source
The combination of continuous flow technology and visible light photocatalysis has been used to improve the safety and productivity of reactions with diazonium salts as reactive intermediates. This approach has proven to be a reliable method for various organic synthesis routes with diazonium salts under mild and well‐defined conditions.
Christoph Deckers, Thomas H. Rehm
wiley +1 more source