Trace metal requirements for microbial enzymes involved in the production and consumption of methane and nitrous oxide [PDF]
Fluxes of greenhouse gases to the atmosphere are heavily influenced by microbiological activity. Microbial enzymes involved in the production and consumption of greenhouse gases often contain metal cofactors.
Glass, Jennifer B., Orphan, Victoria J.
core +3 more sources
Discovery of superoxide reductase: an historical perspective [PDF]
For more than 30 years, the only enzymatic system known to catalyze the elimination of superoxide was superoxide dismutase, SOD. SOD has been found in almost all organisms living in the presence of oxygen, including some anaerobic bacteria, supporting the notion that superoxide is a key and general component of oxidative stress. Recently, a new concept
arxiv +1 more source
One of the ultimate objectives of de novo protein design is to realize systems capable of catalyzing redox reactions on substrates. This goal is challenging as redox-active proteins require design considerations for both the reduced and oxidized states ...
M. Tegoni+4 more
semanticscholar +1 more source
Research Progress of Nitrite Metabolism in Fermented Meat Products
Nitrite is a common color and flavor enhancer in fermented meat products, but its secondary amines may transfer to the carcinogen N-nitrosamines. This review focuses on the sources, degradation, limitations, and alteration techniques of nitrite.
Qiyuan Shen+7 more
doaj +1 more source
Sampling of conformational ensemble for virtual screening using molecular dynamics simulations and normal mode analysis [PDF]
Aim: Molecular dynamics simulations and normal mode analysis are well-established approaches to generate receptor conformational ensembles (RCEs) for ligand docking and virtual screening. Here, we report new fast molecular dynamics-based and normal mode analysis-based protocols combined with conformational pocket classifications to efficiently generate
arxiv +1 more source
Exploring the Molecular Pathways Underlying the Anti‐Diabetic Effects of Millets
Millet consumption may modulate gluconeogenesis and glycolysis, enhance glucose transporter activity, increase leptin levels, inhibit the NF‐κB pathway, and mitigate oxidative and nitrosative stress. ABSTRACT Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemic conditions resulting from inadequate insulin production or ...
Akash Kumar+5 more
wiley +1 more source
Centrifugation of a homogenate made from Pisum arvense L. roots in a sucrose density gradient enabled the separation of the plastid fraction from mitochondria and microsomes.
Genowefa Kubik-Dobosz, Grażyna Kłobus
doaj +1 more source
Influence of oxidative stress produced by nitrite in the activity of methaemoglobin reductase in two different species of fish [PDF]
Nitrite induces the oxidation of the haemoglobin forming methaemoglobin, which is nonfunctional. To oppose this formation fishes have an enzyme that reverses the process called methaemoglobin reductase.
Aníbal, J., Bicho, M.
core
Synthetic and Evolutionary Construction of a Chlorate-Reducing Shewanella oneidensis MR-1. [PDF]
UnlabelledDespite evidence for the prevalence of horizontal gene transfer of respiratory genes, little is known about how pathways functionally integrate within new hosts.
Carlson, Hans K+5 more
core +3 more sources
Direct Electrochemistry of Shewanella oneidensis Cytochrome c Nitrite Reductase
Shewanella oneidensis cytochrome c nitrite reductase (soNrfA) is a dimeric enzyme that plays a key role in bacterial nitrate respiration. The periplasmic reductase catalyzes the six‐electron reduction of nitrite to ammonia but can also catalyze the two ...
Evan T. Judd, S. Elliott
semanticscholar +1 more source