Results 61 to 70 of about 292,870 (340)

Polyethylene Glycol Camouflaged Earthworm Hemoglobin. [PDF]

, 2017
Nearly 21 million components of blood and whole blood and transfused annually in the United States, while on average only 13.6 million units of blood are donated. As the demand for Red Blood Cells (RBCs) continues to increase due to the aging population,
Cabrales, Pedro, Dantsker, David, Friedman, Joel M, Jani, Vivek P, Jelvani, Alborz, Moges, Selamawit, Nacharaju, Parimala, Palmer, Andre, Roche, Camille   +8 more
core   +3 more sources

The key role of nitric oxide in hypoxia: hypoxic vasodilation and energy supply-demand matching [PDF]

, 2013
Significance: a mismatch between energy supply and demand induces tissue hypoxia with the potential to cause cell death and organ failure. Whenever arterial oxygen concentration is reduced, increases in blood flow - 'hypoxic vasodilation' - occur in an ...
Alex Dyson, Audibert G, Berne RM, Blitzer ML, Boutilier RG, Brown IP, Devlin C, Furukawa K, Hall JE, Heyes MP, Jekabsone A, Lehninger A, Leone AM, Louis CA, Martin Feelisch, Mervyn Singer, Michele Umbrello, Modin A, Munk VC, Pohl U, Rengasamy A, Rengasamy A, Vallance P, Whorton AR   +23 more
core   +1 more source

The NAD(P)H:flavin oxidoreductase from Escherichia coli. Evidence for a new mode of binding for reduced pyridine nucleotides [PDF]

The journal of biological chemistry, American Society for Biochemistry and Molecular Biology, 1999, 274, pp.18252-60, 2015
The NAD(P)H:flavin oxidoreductase from Escherichia coli, named Fre, is a monomer of 26.2 kDa that catalyzes the reduction of free flavins using NADPH or NADH as electron donor. The enzyme does not contain any prosthetic group but accommodates both the reduced pyridine nucleotide and the flavin in a ternary complex prior to oxidoreduction.
arxiv   +1 more source

Opportunities for mesoporous nanocrystalline SnO2 electrodes in kinetic and catalytic analyses of redox proteins [PDF]

, 2009
PFV (protein film voltammetry) allows kinetic analysis of redox and coupled-chemical events. However, the voltammograms report on the electron transfer through a flow of electrical current such that simultaneous spectroscopy is required for chemical ...
Angove, Armstrong, Astuti, Astuti, Bamford, Chen, Gemma L. Kemp, Gwyer, James R. Durrant, Jones, Julea N. Butt, Li Xiaoe, Marritt, Myles R. Cheesman, Sophie J. Marritt, Topoglidis, van Wonderen   +16 more
core   +1 more source

Probing a Complex of Cytochromecand Cardiolipin by Magnetic Circular Dichroism Spectroscopy: Implications for the Initial Events in Apoptosis [PDF]

, 2011
Oxidation of cardiolipin (CL) by its complex with cytochrome c (cyt c) plays a crucial role in triggering apoptosis. Through a combination of magnetic circular dichroism spectroscopy and potentiometric titrations, we show that both the ferric and ferrous
Armstrong F. A., Barker P. D., Basova L. V., Battistuzzi G., Battistuzzi G., Belikova N. A., Belikova N. A., Bradley J. M., Bushnell G. W., Cheesman M. R., Cheesman M. R., Ferrer J. C., Foote N., Gadsby P. M. A., Gadsby P. M. A., Gary Silkstone, Hendriks J. H. M., Jing W. G., Julea N. Butt, Justin M. Bradley, Kagan V. E., Kagan V. E., Kalanxhi E., Kapetanaki S. M., Kapralov A. A., Marritt S. J., Michael T. Wilson, Millis K. K., Myles R. Cheesman, Nantes I. L., Oganesyan V. S., Petrovic J., Pettigrew G. W., Pond A. E., Rawlings J., Rigby S. E. J., Rytomaa M., Salamon Z., Sinibaldi F., Sutherland J., Tezcan F. A., Wackerbarth H., Zucchi M. R.   +42 more
core   +1 more source

Nitrite Reductase and Nitric-oxide Synthase Activity of the Mitochondrial Molybdopterin Enzymes mARC1 and mARC2*

Journal of Biological Chemistry, 2014
Background: Nitrite reduction pathways are critical for biological NO production under hypoxia. Results: The mitochondrial enzyme mARC reduces nitrite to NO using cytochrome b5 as electron donor.
C. Sparacino-Watkins, J. Tejero, Bin Sun, M. Gauthier, J. Thomas, Venkata Ragireddy, Bonnie A. Merchant, Jun Wang, Ivan Azarov, P. Basu, M. Gladwin   +10 more
semanticscholar   +1 more source

Residues in the Distal Heme Pocket of Arabidopsis Non-Symbiotic Hemoglobins: Implication for Nitrite Reductase Activity [PDF]

, 2016
It is well-established that plant hemoglobins (Hbs) are involved in nitric oxide (NO) metabolism via NO dioxygenase and/or nitrite reductase activity. The ferrous-deoxy Arabidopsis Hb1 and Hb2 (AHb1 and AHb2) have been shown to reduce nitrite to NO under
Astegno, Alessandra, Chen, Jian, Dominici, Paola, Giorgetti, Alejandro, Kumar, Nitin   +4 more
core   +5 more sources

An integrated biochemical system for nitrate assimilation and nitric oxide detoxification in Bradyrhizobium japonicum [PDF]

, 2016
Rhizobia are recognized to establish N(2)-fixing symbiotic interactions with legume plants. Bradyrhizobium japonicum, the symbiont of soybeans, can denitrify and grow under free-living conditions with nitrate (NO(3)(−)) or nitrite (NO(2)(−)) as sole ...
Alderton, Ana Salas, Andrew J. Gates, Angelo, Bates, Bedmar, Bedmar, Bergersen, Cabrera, Crutzen, David J. Richardson, Delgado, Delgado, Egelhoff, Eulogio J. Bedmar, Franck, Fukuda, Gardner, Gates, Gilberthorpe, Goddard, Hauser, Hernández-Urzúa, Horchani, Inaba, Juan J. Cabrera, Kaneko, Kartal, Kato, Kim, Lin, Luque-Almagro, Luque-Almagro, Maia, Maia, María J. Delgado, María J. Torres, Meakin, Meakin, Mesa, Miller, Mills, Moreno-Vivián, Moreno-Vivián, Nicholas, Pino, Pittman, Poole, Pullan, Ravishankara, Regensburger, Rinaldo, Robles, Rowley, Sambrook, Schinko, Simon, Spiro, Spiro, Sánchez, Sánchez, Sánchez, Tinajero-Trejo, Torres, Torres, Vargas, Velasco, Vine, Vine, Zumft   +69 more
core   +1 more source

The stability of 3 transmembrane and 4 transmembrane human vitamin K epoxide reductase models [PDF]

, 2016
3 transmembrane and 4 transmembrane helices models are suggested for the human vitamin K epoxide reductase (VKOR). In this study, we investigate the stability of the human 3 transmembrane/4 transmembrane VKOR models employing a coarse-grained normal mode analysis and molecular dynamics simulation.
arxiv   +1 more source

Molecular dynamics simulation of the order-disorder phase transition in solid NaNO$_2$ [PDF]

Physical Review B 68, 174106 (2003), 2003
We present molecular dynamics simulations of solid NaNO$_2$ using pair potentials with the rigid-ion model. The crystal potential surface is calculated by using an \emph{a priori} method which integrates the \emph{ab initio} calculations with the Gordon-Kim electron gas theory.
arxiv   +1 more source