Results 61 to 70 of about 28,308 (276)

Orientation and Alignment in the Photodissociation of Alkyl Nitrites

, 2022
vii, 19 p.The photodissociation of alkyl nitrites (RONO) provides a view of fundamental processes in chemical dynamics. A primary product in the photodissociation, NO, is readily amenable to 1+1’ REMPI, allowing for a detailed view of the translational ...
Tye, Oliver J.
core   +1 more source

Breakthrough Design of Highly Potent Antivirals Against Wild‐Type HIV‐1 and Lenacapavir‐Resistant M66I Variant

Angewandte Chemie, EarlyView.
Lenacapavir, the first‐in‐class drug targeting HIV‐1 capsid, is a breakthrough drug in HIV‐1 treatment and prophylaxis. However, a single M66I mutation confers complete viral resistance to lenacapavir. We report herein the design and synthesis of innovative R2 analogs demonstrating low nM potency against HIV‐1 M66I and excellent pharmacokinetics in ...
Nicolas Jamey, D. M. Nirosh Udayanga, Huanchun Zhang, Roshan Katekar, Wei Xie, Shreya M. Ravichandran, Xinyong Cai, Zachary C. Lorson, William M. McFadden, Won Hee Ryu, Jiashu Xie, Karen A. Kirby, Stefan G. Sarafianos, Zhengqiang Wang   +13 more
wiley   +2 more sources

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

Advanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai, Pengchong Du, Zhaoyang Wang, Surilige, Rangga Fokta, Renjian Tan, Xiqing Zhao, Shuoyi Zhang, Yuecheng Wang, Yixin Zhang, Ziliang Fu, Rui Gong, Cheng Jiang, Yisheng He, Qiguang Wang, Renke Li, Khoon Lim, Junnan Tang, Xiaolin Cui   +18 more
wiley   +1 more source

Effect of the microbial activity on nitrification in soils cultivated with Brachiaria humidicola (Rendle) Schweicerdt in Cerete, Cordoba

Temas Agrarios, 2015
Nitrogen fertilizers used in agriculture have increased the emissions of nitrogen oxides to the atmosphere. This study evaluated the production of NO2 - (nitrite) and N03 - (nitrate) by soilborne bacteria during the dry and the rainy seasons in The ...
Liliana Grandett, Sony Reza, Juan De Dios Jaraba Navas, Yuri Pardo   +3 more
doaj   +1 more source

Liquid Gallium Nanozyme Coatings Enable Sustained Nitric Oxide Generation With Antioxidant and Anti‐Inflammatory Functions

Advanced Science, EarlyView.
Liquid gallium (Ga) acts as a catalytic center for nitric oxide (NO) generation within a tannic acid–zirconium metal–phenolic network coating. Stabilized Ga nanoparticles catalyze S‐nitrosothiol decomposition through surface electron transfer, enabling controlled NO production, enhancing endothelial biocompatibility, and providing antioxidant and anti ...
Franco Centurion, Kang Lin, Shu Geng, Siti Nur Asyura Adzlan, Qingqing Fan, Federico Mazur, Ravindra Kokate, Priyank Kumar, Christina Cortez‐Jugo, Frank Caruso, Rona Chandrawati   +10 more
wiley   +1 more source

Solvent‐Induced Structural Modulation in Nanoscale Covalent Organic Frameworks Enables High‐Performance NO2 Sensing

Angewandte Chemie, EarlyView.
Solvent intercalation disrupts the stacking order of protonated porphyrin‐based 2D COF nanoparticles, resulting in a less compactly packed structure with increased accessibility of porphyrin sites. This structural modulation leads to significantly enhanced chemiresistive NO2 sensing performance.
Yu Pan, Xueying Kong, Guangling Liang, Samson Afewerki, Chao Xu   +4 more
wiley   +2 more sources

Association of salivary biochemical parameters with etiopathogenetic variants of laryngopharyngeal reflux in young adult men: a single-centre cross-sectional observational study

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki
Aim. To verify salivary biochemical parameters (pH, NO2–/NOS, –SH groups, protein carbonyls – aldehyde and ketone phenylhydrazones (APH, KPH)) and heart rate variability (HRV) indices (SDNN, SI, LF/HF, TP, PARS) according to etiopathogenetic LPR ...
V. M. Kryshtal , O. V. Hancheva
doaj   +1 more source

Influence of “Vitakorm-BSR-Forte” preparation on the antioxidant and cytoprotective processes in the mucosa of small intestine under the action of aflatoxin B1

Біологічні студії, 2016
The mechanism of aflatoxin B1 influence on the cells of small intestine mucosa and the possibility of correction and prevention of metabolic disorders in animals using “Vitakorm-BSR-Forte” phytopreparation was investigated. Intragastrial administration
I. V. Panchuk, G. L. Antonyak
doaj   +1 more source

VEGF is indirectly associated with NO production

, 2012
Background? Increased levels of vascular endothelial growth factor (VEGF) have been observed in patients with metabolic syndrome (MetS). Nitric oxide (NO) formation is reduced in MetS, but its relationship to VEGF production remains poorly defined.
Feelisch, Martin, Bluck, Les J. C., Bluck, Les C.J., Tomatis, Virginia, Siervo, Mario, Stephan, Blossom C. M., Blossom, C.M. Stephen   +6 more
core   +1 more source

A Photothermally Amplified Enzyme–Nitric Oxide Co‐Regulatory System Reprograms Pathological ECM–Fibroblast Crosstalk to Alleviate Hypertrophic Scarring

Advanced Science, EarlyView.
An enzyme–nitric oxide (NO) co‐regulatory strategy reprograms pathological extracellular matrix (ECM)–fibroblast crosstalk in hypertrophic scars. Enzymatic degradation of pre‐existing ECM relieves aberrant mechanical cues, while NO‐mediated fibroblast phenotypic modulation restrains excessive collagen synthesis.
Junzhe Fu, Fan Jia, Yixian Mu, Wanzhe Liu, Dingqi Tang, Qiao Jin, Jian Ji, Youxiang Wang   +7 more
wiley   +1 more source