Results 11 to 20 of about 1,962 (128)

Conserved Active Site Loop Residues of E. coli DinB and Human DNA Polymerase Kappa Govern Activity. [PDF]

Environ Mol Mutagen
ABSTRACT DNA damage is ubiquitous and can arise from numerous sources. To mitigate the potential effects of DNA damage, cells possess varied DNA repair and damage tolerance mechanisms. Conserved throughout evolution, specialized DNA damage‐bypass DNA polymerases from the Y family provide DNA damage tolerance. E.
Antczak NM, Ippoliti P, Ahn J, Kankanamge LP, Dudko T, Balfour-Jeffrey K, Pancoe B, MacDiarmid Z, Pham CM, Williams D, Mora A, Walsh JM, Beuning PJ.   +12 more
europepmc   +2 more sources

Structural basis of ligand selectivity in FAD/NAD(P)H-dependent dehydrogenases: insights from trypanothione reductase and type II NADH dehydrogenase. [PDF]

Protein Sci
Abstract FAD/NAD(P)H‐dependent dehydrogenases form a structurally conserved family of redox enzymes that participate in essential metabolic processes across parasites and higher organisms. Among them, trypanothione reductase (TR) is a key component of the redox metabolism of Leishmania species and represents an attractive target for antileishmanial ...
Perrone GCM, Spadone S, Francavilla AL, Morselli S, Todisco S, Ortalli M, Mendoza-Roldan JA, Scaglione V, Sgobba MN, Guerra L, Belluti F, Varani S, Otranto D, De Grassi A, Volpicella M, Pierri CL.   +15 more
europepmc   +2 more sources

Wound-Healing Efficacy of <i>Garcinia pedunculata</i> Fruit Extract: In Vivo and In Silico Validation of Regenerative Mechanisms With Histological Analysis. [PDF]

Food Sci Nutr
This study demonstrates that G. pedunculata fruit possesses potent wound‐healing activity, evidenced by accelerated wound contraction, reduced epithelialization time, enhanced fibroblast proliferation, increased collagen deposition, and improved neovascularization in both excision and burn models. ABSTRACT Garcinia pedunculata Roxb., traditionally used
Tahrim KS, Rahman MM, Rahman MS, Sayem MA, Momen MSH, Hasan T, Mamun MJI, Hasan MM.   +7 more
europepmc   +2 more sources

Development and Validation of a Stability-Indicating HPTLC-Based Assay for the Quantification of Nitrofurazone Ointment [PDF]

Molecules
This paper reports on a validated, stability-indicating high-performance thin-layer chromatography (HPTLC)-based assay for the quantification of nitrofurazone in an ointment formulation.
K. M. Yasif Kayes Sikdar, Hayley Andrews, Kate Pacecca, Aliyah Petker, Sarah Samie, Tomislav Sostaric, Lee Yong Lim, Md Khairul Islam, Cornelia Locher   +8 more
doaj   +2 more sources

Postoperative Dressing Regimens in Nail Surgeries: A Scoping Review. [PDF]

J Foot Ankle Res
ABSTRACT Background Toenail surgeries are one of the most common surgeries performed on the lower limb with many common postoperative complications, including prolonged healing time, infection and prolonged exudation. There is a wide variety of dressings designed to reduce the rate of postoperative complications and improve healing.
Wassef DYFI, Al-Modhefer Z, Hennessy K.
europepmc   +2 more sources

Cloning, purification and possible use of a Bacillus nitroreductase in biotechnological applications [PDF]

Scientific Reports
Nitroreductases (NRs) can reduce nitroaromatic compounds, which are toxic, mutagenic or carcinogenic, to nitrite, amino group or hydroxylamine groups. We have utilised a cloned nitroreductase from a moderate thermophilic Bacillus species in E. coli BL21.
Firdevs Rozan Tuşar Demir, Kemal Güven, Fatma Matpan Bekler, Reyhan Gül Güven, Pınar Küce Çevik, Mustafa Abdullah Yilmaz, Seçil Yalaz   +6 more
doaj   +2 more sources

Progress in Electrode Materials for the Detection of Nitrofurazone and Nitrofurantoin [PDF]

Biosensors
Recently, it has been found that electrochemical sensing technology is one of the significant approaches for the monitoring of toxic and hazardous substances in food and the environment.
Mohammad Aslam, Saood Ali, Khursheed Ahmad, Danishuddin   +3 more
doaj   +2 more sources

Highly thermostable RhB@Zr-Eddc for the selective sensing of nitrofurazone and efficient white light emitting diode [PDF]

Frontiers in Chemistry
Highly thermostable RhB@Zr-Eddc composites with the Rhodamine B (RhB) enclosed into the nanocages of Zr-Eddc was synthesized by one-pot method under hydrothermal conditions, whose structure, morphology and stability were characterized through the X-ray ...
Yanqiong Shen, Di Ma, Mian Zhao, Jinjie Qian, Qipeng Li   +4 more
doaj   +2 more sources

Pectin-modified PCN-222 for detecting nitrofurazone residues with dual signals in livestock, poultry, and aquatic products [PDF]

Food Chemistry: X
Nitrofurazone and its metabolite semicarbazide (SEM) residues present in food products pose substantial health hazards to humans. Herein, the colorimetric–fluorescent lateral flow immunoassay (LFIA) for 4[(4-carboxyphenyl)-methylene]-hydrazinecarboxamide
Keyu Du, Jie Shen, Siyao Zhong, Hefei Wang, Yulou Qiu, Xuping Shentu, Xiaoping Yu, Zihong Ye, Haizhi Huang   +8 more
doaj   +2 more sources

Molecular conformational evolution mechanism during nucleation of crystals in solution

IUCrJ, 2020
Nucleation of crystals from solution is fundamental to many natural and industrial processes. In this work, the molecular mechanism of conformational polymorphism nucleation and the links between the molecular conformation in solutions and in crystals ...
Xin Li, Na Wang, Jinyue Yang, Yunhai Huang, Xiongtao Ji, Xin Huang, Ting Wang, Honghai Wang, Hongxun Hao   +8 more
doaj   +1 more source