We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins +9 more
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Sugar-induced cell death (SICD) in <i>Saccharomyces cerevisiae</i>: insights into nitrogen-mediated rescue and apoptotic cell death pathways. [PDF]
Parbhudayal R, Cheng HP.
europepmc +1 more source
Industrial-grade nitrogen sources modulate CaCO3 polymorphs and strength in MICP-cemented sand: A structure-property study. [PDF]
Zhang Y +8 more
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Effect of Nutrient Enrichment on Alpha and Beta Diversity of Macroinvertebrate Community in a Boreal River of Northern China. [PDF]
Sun X +9 more
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Metabolic Responses of <i>Candida viswanathii</i> on Lipase Production: Influence of Carbon Sources and Culture System. [PDF]
de Oliveira NML +9 more
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Regulatory Effects of "Straw-Nitrogen Fertilizer" on Maize Yield Enhancement. [PDF]
Zhang Y +5 more
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Effects of deep slow-release fertilizer on melon yield, economic benefits and rhizosphere microorganisms. [PDF]
Yan M +6 more
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Absolute values of the coupling constants 1J(15N15N), 1J(15NH) of six phenylhydrazones forming hydrogen bond, 2J(15N15NH) of four, and 4J(15NH) of two phenylhydrazones have been determined. Three coupling constants 1J(15N15N) have been obtained from the nitrogen-15 monolabelled compounds by measuring the other nitrogen at natural abundance.
Antonín Lyčka, Dobroslav Šnobl
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Nitrogen-15: Microbiological Alteration of Abundance
Science, 1968The abundance of N 15 relative to N 14 is significantly altered during experiments in vitro in which nitrate and nitrite are microbiologically reduced to nitrogen gas. In all studies to date, N 14 O 3 - and N 14
R P, Wellman, F D, Cook, H R, Krouse
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