Results 191 to 200 of about 1,112,497 (266)

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

open access: yesAdvanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins   +9 more
wiley   +1 more source

Metabolic Responses of <i>Candida viswanathii</i> on Lipase Production: Influence of Carbon Sources and Culture System. [PDF]

open access: yesACS Omega
de Oliveira NML   +9 more
europepmc   +1 more source

Coupling constants nitrogen-15-nitrogen-15 and nitrogen-15-hydrogen in phenylhydrazones forming hydrogen bond

Collection of Czechoslovak Chemical Communications, 1981
Absolute values of the coupling constants 1J(15N15N), 1J(15NH) of six phenylhydrazones forming hydrogen bond, 2J(15N15NH) of four, and 4J(15NH) of two phenylhydrazones have been determined. Three coupling constants 1J(15N15N) have been obtained from the nitrogen-15 monolabelled compounds by measuring the other nitrogen at natural abundance.
Antonín Lyčka, Dobroslav Šnobl
openaire   +1 more source

Nitrogen-15: Microbiological Alteration of Abundance

Science, 1968
The abundance of N 15 relative to N 14 is significantly altered during experiments in vitro in which nitrate and nitrite are microbiologically reduced to nitrogen gas. In all studies to date, N 14 O 3 - and N 14
R P, Wellman, F D, Cook, H R, Krouse
openaire   +2 more sources

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