Results 91 to 100 of about 4,736,631 (400)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Analysis of intermolecular interactions in homologous molecular crystals of energetic materials
Energetic Materials Frontiers, 2020 s: Crystal packing modes determine the energy and safety performance of energetic materials (EMs) to some extent. To deepen the understanding of the intermolecular interactions in the crystal packings, the homologous molecular crystals of energetic ...
Yilin Cao +4 more
doaj
A Measurement of the Absorption of Liquid Argon Scintillation Light by Dissolved Nitrogen at the Part-Per-Million Level [PDF]
, 2013 We report on a measurement of the absorption length of scintillation light in liquid argon due to dissolved nitrogen at the part-per-million (ppm) level.
Chiu, C. S. +5 more
core +2 more sources
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
On the origin of nitrogen [PDF]
Astronomy & Astrophysics, 2002 The problem of the origin of nitrogen is considered within the framework of an empirical approach. The oxygen abundances and nitrogen to oxygen abundances ratios are derived in HII regions of a number of spiral galaxies through the recently suggested P-method using more than six hundred published spectra.
L. S. Pilyugin +2 more
openaire +4 more sources
Core-level photoemission spectroscopy of nitrogen bonding in GaNxAs1–x alloys [PDF]
, 2004 The nitrogen bonding configurations in GaNxAs1–x alloys grown by molecular beam epitaxy with 0.07=0.03, the nitrogen is found to exist in a single bonding configuration – the Ga–N bond; no interstitial nitrogen complexes are present.
C. F. McConville +5 more
core +1 more source
Molecular Oncology, EarlyView.Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source
Effect of Nitrogen Fertilizer Dose and Application Timing on Yield and Nitrogen Use Efficiency of Irrigated Hybrid Rice under Semi-Arid Conditions [PDF]
, 2019 Nitrogen fertilizer is the major input in rice production and the optimum rate and application timing management assure profitability and sustainability of the production system.
Ametonou, F.Y. +5 more
core
Nitrogen Induced Ferromagnetism In Cobalt Doped BaTiO3 [PDF]
, 2012 The electronic structure and magnetism of Cobalt doped BaTiO3 (BaTi1-xCoxO3) is investigated. Substitutional Nitrogen on an Oxygen site is found to play an important role in inducing net magnetic moments in the system.
Mitra, C.
core +2 more sources
Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source