Results 91 to 100 of about 3,460,426 (309)

Nitrogen uptake and the importance of internal nitrogen loading in Lake Balaton [PDF]

open access: yes, 2001
1. The importance of various forms of nitrogen to the nitrogen supply of phytoplankton has been investigated in the mesotrophic eastern and eutrophic western basin of Lake Balaton.<br /> 2.
Herodek, S.   +3 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Measures to achieve a stable farming system in sustainable agriculture – a short review

open access: yesAnnales Universitatis Paedagogicae Cracoviensis Studia Naturae, 2019
Zrównoważony system rolny jest najlepszym sposobem na zaspokojenie potrzeb dzisiejszych i przyszłych pokoleń. W systemie tym wielkość plonu wzrasta wraz z zastosowaniem upraw międzyrzędowych, poprzez wyższy współczynnik wzrostu roślin, redukcję nasion ...
Mohamad Hesam Shahrajabian   +2 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

NPBS Atlas: a comprehensive data resource for exploring the biological sources of natural products

open access: yesJournal of Cheminformatics
Natural products continue to play a pioneering role in drug discovery due to their extraordinary chemical and biological diversity. However, their full therapeutic potential remains largely underutilized, hindered by the fragmented documentation of ...
Tingjun Xu   +6 more
doaj   +1 more source

Nitrogen fixation and soil nitrogen in organic ley arable rotations [PDF]

open access: yes, 2002
This report was presented at the UK Organic Research 2002 Conference. Nitrogen (N) fixation in a white clover/ryegrass mixture was measured in 1,2,3 and 4-year-old organically managed leys during 2000.
Atkinson, David   +3 more
core  

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Delayed crystallization response-inspired waterborne polyurethane with high performance

open access: yesNature Communications
Waterborne polyurethane elastomers (WPUE), synthesized in aqueous solutions, represent a revolutionary sustainable alternative to thermoplastic polyurethane elastomers (TPUE), which are typically produced using organic solvent.
Chenxi Huyan   +10 more
doaj   +1 more source

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