Results 51 to 60 of about 467,905 (267)
THE DETERMINATION OF NITROGEN IN ORGANIC COMPOUNDS. [PDF]
Journal of the American Chemical Society, 1904 n ...
Sherman, H. C., Falk, M. J.
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Classical QSAR and Docking Simulation of 4-Pyridone Derivatives for Their Antimalarial Activity
Molecules, 2018 In this work, the minimum energy structures of 22 4-pyridone derivatives have been optimized at Density Functional Theory level, and several quantum molecular, including electronic and thermodynamic descriptors, were computed for these substrates in ...
Máryury Flores-Sumoza +5 more
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YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Catabolism of Nitrogenous Compounds by Pseudomonas [PDF]
Journal of General Microbiology, 1962 SUMMARY: The rate of O2 utilization by both pigmented and non-pigmented strains of Pseudomonas aeruginosa was greater with 2 % (w/v) Casitone as substrate than with 0.1 M-glucose as substrate. P. aeruginosa readily catabolized Casitone, amino acids and other nitrogenous compounds with the production of an alkaline reaction even in the presence of 0.5% (
W L, GABY, C, LOGAN, S, WHITAKER
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FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline
FEBS Open Bio, EarlyView.Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey +4 more
wiley +1 more source
The Influence of Biopolym FTZ on the Content of Nitrogen Compounds in Rumen
Scientific Papers Animal Science and Biotechnologies, 2023 The aim of this study was to verify the effect of Biopolym FZT on the crude protein in the ruminal content. The experiment was conducted in laboratory conditions. Rumen content was removed from the Holstein breed cow fitted with ruminal fistula.
Eva Petrovičová +4 more
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