Results 61 to 70 of about 338,113 (255)

Atmospheric Inorganic Nitrogen Deposition and Its Influence on the Coastal Water Nutrients in Xiamen

Atmosphere
Atmospheric nitrogen deposition in coastal areas has a significant impact on water nutrients, with increasing emission of atmospheric nitrogen-containing pollutants.
Jiehua Hu, Shuhui Zhao, Siying Dai, Rong Tian, Yang Luo, Shanshan Wang, Hanyue Xu, Xiaoke Zhang, Xia Sun, Shiyu Shen, Qisheng Zeng, Jinpei Yan   +11 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Atmospheric deposition of nitrogen and sulphur in relation to critical loads of nitrogen and acidity in the Czech Republic

Journal of Forest Science, 2006
Estimates of dry and wet deposition of sulphur and nitrogen were compared with critical loads of sulphur and nitrogen in the Czech Republic on 1 ×1 km grid.
M. Zapletal
doaj   +1 more source

Temporal-spatial dynamics in orthoptera in relation to nutrient availability and plant species richness. [PDF]

PLoS ONE, 2013
Nutrient availability in ecosystems has increased dramatically over the last century. Excess reactive nitrogen deposition is known to negatively impact plant communities, e.g. by changing species composition, biomass and vegetation structure. In contrast,
Rob J J Hendriks, Luisa G Carvalheiro, Roy M J C Kleukers, Jacobus C Biesmeijer   +3 more
doaj   +1 more source

Application of CrAlN coatings on carbide substrates in routing of MDF [PDF]

, 2007
This study deals with the development of Chromium Aluminium Nitride (CrAlN) hard coatings (by varying the nitrogen content in the plasma, the target bias voltage, the working pressure and the deposition time) and their characterization by physical and ...
COLLET, Robert, DJOUADI, Mohamed Abdou, FERREIRA-MARTIN, Jean-Pierre, LABIDI, Chafik, NOUVEAU, Corinne   +4 more
core   +5 more sources

Nitrogen Emission and Deposition: The European Perspective [PDF]

The Scientific World JOURNAL, 2001
Europe has been successful in reducing the emissions of several nitrogenous pollutants over recent decades. This is reflected in concentrations and deposition rates that have decreased for several components. Emissions of nitrogen containing gases are estimated to have decreased in Europe by 10%, 21%, and 14% for NO, NOx, and NH3, respectively, between
Jan Willem Erisman, Peringe Grennfelt, Mark Sutton   +2 more
openaire   +3 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Effects of Grazing Sheep and Mowing on Grassland Vegetation Community and Soil Microbial Activity under Different Levels of Nitrogen Deposition

Agriculture, 2022
Increasing nitrogen deposition plays a critical role in the material circulation of grassland. Mowing and grazing sheep are important means of utilizing grassland.
Chengyang Zhou, Shining Zuo, Xiaonan Wang, Yixin Ji, Qiezhuo Lamao, Li Liu, Ding Huang   +6 more
doaj   +1 more source

Nature of Nitrogen Incorporation in BiVO4 Photoanodes through Chemical and Physical Methods [PDF]

, 2019
In recent years, BiVO4 has been optimized as a photoanode material to produce photocurrent densities close to its theoretical maximum under AM1.5 solar illumination. Its performance is, therefore, limited by its 2.4 eV bandgap.
Abdi, Fatwa F., Ahmet, Ibbi Y., Berglund, Sean P., Boettger, Roman, Bogdanoff, Peter, Cavallo, Luigi, Dubourdieu, Catherine, Harb, Moussab, Hoehn, Christian, Irani, Rowshanak, Jang, Ji-Wook, Lardhi, Sheikha, Plate, Paul, Schmitt, Sebastian W., van de Krol, Roel   +14 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source