Results 61 to 70 of about 1,677,076 (289)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Atmospheric Inorganic Nitrogen Deposition and Its Influence on the Coastal Water Nutrients in Xiamen

Atmosphere
Atmospheric nitrogen deposition in coastal areas has a significant impact on water nutrients, with increasing emission of atmospheric nitrogen-containing pollutants.
Jiehua Hu, Shuhui Zhao, Siying Dai, Rong Tian, Yang Luo, Shanshan Wang, Hanyue Xu, Xiaoke Zhang, Xia Sun, Shiyu Shen, Qisheng Zeng, Jinpei Yan   +11 more
doaj   +1 more source

Arbuscular mycorrhizal fungi inoculation exerts weak effects on species- and community-level growth traits for invading or native plants under nitrogen deposition

Frontiers in Ecology and Evolution, 2023
Nitrogen deposition and biological invasion are two major components of global environmental change. Nitrogen deposition has been considered to enhance the resource availability of recipient habitats, which influences the invasiveness of plant invader ...
Xiao Guo, Mingyan Li, Siyu Jiang, Liyu Yang, Shaoxia Guo, Lijun Xing, Tong Wang   +6 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Temporal-spatial dynamics in orthoptera in relation to nutrient availability and plant species richness. [PDF]

PLoS ONE, 2013
Nutrient availability in ecosystems has increased dramatically over the last century. Excess reactive nitrogen deposition is known to negatively impact plant communities, e.g. by changing species composition, biomass and vegetation structure. In contrast,
Rob J J Hendriks, Luisa G Carvalheiro, Roy M J C Kleukers, Jacobus C Biesmeijer   +3 more
doaj   +1 more source

National Atmospheric Deposition Program 2011 Annual summary [PDF]

, 2012
is peer reviewedSubmitted by Susan Braxton (braxton@illinois.edu) on 2013-01-29T22:55:31Z No. of bitstreams: 1 2011as.pdf: 4443124 bytes, checksum: 1e2ff568a6e350fe41bba46c81de3531 (MD5)Made available in DSpace on 2013-01-29T22:55:31Z (GMT). No.
National Atmospheric Deposition Program
core  

Nitrogen deposition and its contribution to nitrogen cycling and associated soil processes [PDF]

, 1998
Human activity has greatly perturbed the nitrogen cycle through increased fixation by legumes, by energy and fertilizer production, and by the mobilization of N from long-term storage pools.
Bradbury, N. J., Willison, T. W., Poulton, P. R., Bailey, N. J., Howe, M., Goulding, K. W. T., Hargreaves, P., Murphy, D. V.   +7 more
core   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source