Results 71 to 80 of about 3,652,527 (299)

Effects of dual deletion of glnR and mtrA on expression of nitrogen metabolism genes in Streptomyces venezuelae

open access: yesMicrobial Biotechnology, 2022
Summary GlnR activates nitrogen metabolism genes under nitrogen‐limited conditions, whereas MtrA represses these genes under nutrient‐rich conditions in Streptomyces. In this study, we compared the transcription patterns of nitrogen metabolism genes in a
Yanping Zhu   +5 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Regulatory networks controlling nitrogen sensing and uptake in Candida albicans. [PDF]

open access: yesPLoS ONE, 2014
Nitrogen is one of the key nutrients for microbial growth. During infection, pathogenic fungi like C. albicans need to acquire nitrogen from a broad range of different and changing sources inside the host.
Shruthi Ramachandra   +5 more
doaj   +1 more source

Nitrogen-Centered Concave Molecules with Double Fused Pentagons

open access: yes, 2019
Distinctive concave compounds bearing a nitrogen core and double fused pentagons were synthesized with a palladium-catalyzed intramolecular coupling of 1-chloro-8H-indolo­[3,2,1-de]­acridine as the key step. Structural analysis confirmed the formation of
Gang Zhang (279544)   +1 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Management of Seeding Rate and Nitrogen Fertilization for Lodging Risk Reduction and High Grain Yield of Mechanically Direct-Seeded Rice under a Double-Cropping Regime in South China

open access: yesAgronomy
Precision hill-drop direct seeding using mechanical drilling is a unique direct seeding technique employed in south China that offers advantages such as excellent grain yield and high lodging resistance.
Longmei Wu   +6 more
doaj   +1 more source

Replication Data for: The Whistleblower Industrial Complex

open access: yes, 2023
This page contains the data necessary to replicate the results of "The Whistleblower Industrial Complex" by Alexander I. Platt, published in the Yale Journal on Regulation (2023)
Yale Journal on Regulation
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Regulation of Nitrogen Pollution: Taxes versus Quotas

open access: yesJournal of Agricultural and Resource Economics, 1995
This paper investigates the effects of first-best policies to regulate nitrogen application. Some nitrogen fertilizer is applied ex ante before a random rainfall, but side-dressed nitrogen may be applied ex post.
E. Kwan Choi, Eli Feinerman
doaj   +1 more source

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