Results 1 to 10 of about 338 (68)

Pleiotropic Effects of PipX, PipY, or RelQ Overexpression on Growth, Cell Size, Photosynthesis, and Polyphosphate Accumulation in the Cyanobacterium Synechococcus elongatus PCC7942

Frontiers in Microbiology, 2023
The cyanobacterial protein PipY belongs to the Pyridoxal-phosphate (PLP)-binding proteins (PLPBP/COG0325) family of pyridoxal-phosphate-binding proteins, which are represented in all three domains of life.
Asuncion Contreras, Khaled A. Selim, Karl Forchhammer   +2 more
exaly   +4 more sources

The Conserved Family of the Pyridoxal Phosphate-Binding Protein (PLPBP) and Its Cyanobacterial Paradigm PipY

Life, 2022
The PLPBP family of pyridoxal phosphate-binding proteins has a high degree of sequence conservation and is represented in all three domains of life. PLPBP members, of which a few representatives have been studied in different contexts, are single-domain ...
Asuncion Contreras, Vicente Rubio, Lorena Tremiño   +2 more
exaly   +4 more sources

PipY, a Member of the Conserved COG0325 Family of PLP-Binding Proteins, Expands the Cyanobacterial Nitrogen Regulatory Network

Frontiers in Microbiology, 2017
Synechococcus elongatus PCC 7942 is a paradigmatic model organism for nitrogen regulation in cyanobacteria. Expression of genes involved in nitrogen assimilation is positively regulated by the 2-oxoglutarate receptor and global transcriptional regulator ...
Asuncion Contreras, Vicente Rubio, Raquel Cantos   +2 more
exaly   +4 more sources

Mutational Analyses Reveal PLP-Independent Functions at PipY, the Cyanobacterial Paradigm for Pyridoxal-Phosphate Binding Proteins

Scientific Reports
Pyridoxal-phosphate binding proteins (PLPBP) are involved in the homeostasis of B6 vitamers and amino/keto acids, share a high degree of sequence conservation and are represented in all three domains of life. Despite the obligate presence of the catalyst
Asuncion Contreras, Lorena Tremiño, Antonio Llop   +2 more
exaly   +3 more sources

Distinctive Features of PipX, a Unique Signaling Protein of Cyanobacteria

Life, 2020
PipX is a unique cyanobacterial protein identified by its ability to bind to PII and NtcA, two key regulators involved in the integration of signals of the nitrogen/carbon and energy status, with a tremendous impact on nitrogen assimilation and gene ...
Asuncion Contreras, Paloma Salinas, Raquel Cantos   +2 more
exaly   +4 more sources

Hydrophilic Poly(Iminopyridinium Ylide)s: Defining a New Chemical Space for Poly(Ylide)s

Macromolecular Rapid Communications
Rising hypersensitivity to PEG and accelerated blood clearance highlight the need for alternative charge‐neutral hydrophilic polymers. Poly(ylide)s represent a class of hydrophilic polymers with biocompatibility and antifouling properties.
Patrick Theato, Kevin Neumann, Alexandra Orlova   +2 more
exaly   +3 more sources

Impact of Physical Exercise Intervention and PPARγ Genetic Polymorphisms on Cardio-Metabolic Parameters Among a Chinese Youth Population

BMJ Open Sport and Exercise Medicine, 2020
Objective Physical inactivity inChinese youth students particularly in senior high schools, who participate inthe National Higher Education Entrance Examination (NCEE) is very common.
Chong Shen, Harvest F Gu, Wanjian Gu
exaly   +4 more sources

Nrf2, a PPARγ alternative pathway to promote CD36 expression on inflammatory macrophages: implication for malaria. [PDF]

PLoS Pathogens, 2011
CD36 is the major receptor mediating nonopsonic phagocytosis of Plasmodium falciparum-parasitized erythrocytes by macrophages. Its expression on macrophages is mainly controlled by the nuclear receptor PPARγ.
David Olagnier, Rose-Anne Lavergne, Etienne Meunier, Lise Lefèvre, Christophe Dardenne, Agnès Aubouy, Françoise Benoit-Vical, Bernhard Ryffel, Agnès Coste, Antoine Berry, Bernard Pipy   +10 more
doaj   +2 more sources

PPARγ ligands switched high fat diet-induced macrophage M2b polarization toward M2a thereby improving intestinal Candida elimination. [PDF]

PLoS ONE, 2010
Obesity is associated with a chronic low-grade inflammation that predisposes to insulin resistance and the development of type 2 diabetes. In this metabolic context, gastrointestinal (GI) candidiasis is common.
Lise Lefèvre, Amandine Galès, David Olagnier, José Bernad, Laurence Perez, Rémy Burcelin, Alexis Valentin, Johan Auwerx, Bernard Pipy, Agnès Coste   +9 more
doaj   +2 more sources

Kinetics of monocyte subpopulations during experimental cerebral malaria and its resolution in a model of late chloroquine treatment

Frontiers in Cellular and Infection Microbiology, 2022
Cerebral malaria (CM) is one of the most severe forms of malaria and is a neuropathology that can lead to death. Monocytes have been shown to accumulate in the brain microvasculature at the onset of neurological symptoms during CM.
Jade Royo, Aissata Camara, Aissata Camara, Benedicte Bertrand, Philippe Batigne, Agnes Coste, Bernard Pipy, Agnes Aubouy, the NeuroCM Group, Dissou Affolabi, Jules Alao, Daniel Ajzenberg, Linda Ayédadjou, Gwladys Bertin, Bibiane Biokou, Farid Boumédiène, Josselin Brisset, Michel Cot, Jean-Eudes Degbelo, Philippe Deloron, Ida Dossou-Dagba, Latifou Dramane, Jean François Faucher, Sandrine Houzé, Sayeh Jafari-Guemouri, Claire Kamaliddin, Elisée Kinkpé, Anaïs Labrunie, Yélé Ladipo, Thomas Lathiere, Achille Massougbodji, Audrey Mowendabeka, Jade Papin, Pierre-Marie Preux, Marie Raymondeau, Darius Sossou, Brigitte Techer, Bertin Vianou, Laurence Watier   +38 more
doaj   +2 more sources