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The biotransformation of nitroglycerin
Biochemical Pharmacology, 1965Abstract The transformation of nitroglycerin (NG) was accomplished by the formation of 1,2- and 1,3-dinitroglycerin. The dinitrates were resistant to further degradation and appeared as the urinary metabolites after the administration of NG. The dinitroglycerins were less active coronary vasodilators and blood pressure depressants than NG.
P, Needleman, J C, Krantz
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Nitroprusside or Nitroglycerin
Annals of Internal Medicine, 1981Excerpt To the editor: Dr. Tillisch (1) proposes nitroprusside as the agent of choice for impedance reduction in the setting of septic shock with depressed cardiac output and substantially elevated...
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