Results 131 to 140 of about 5,219,551 (261)

Fragmentation of Vancoresmycin Reveals a Strong Dependence on Global Molecular Architecture for Antibacterial Activity

open access: yesChemMedChem, Volume 21, Issue 15, 14 August 2026.
Fragmentation of the natural product vancoresmycin reveals an essential role of global architecture for biological potency. Vancoresmycin is a structurally complex tetramic‐acid‐containing natural product with potent activity against Gram‐positive bacteria, yet its structure–activity relationships remain poorly defined.
Max Schönenbroicher   +8 more
wiley   +1 more source

Polydopamine-mediated in situ synthesis of gold nanoparticles uniformly distributed on silk fibers as reusable catalysts for efficient 4-nitrophenol reduction

open access: yesJournal of Industrial Textiles
Developing green fibrous materials with uniformly distributed metal nanoparticles for highly efficient and recyclable catalysis remains a major challenge. Herein, we developed a simple, effective, and green method to immobilize gold nanoparticles (AuNPs)
Zhendong Zhang   +7 more
doaj   +1 more source

Auto‐Click Synthesis of a Copper(I)–N‐Heterocyclic Carbene Porous Organic Polymer and Its Transmetalation to Palladium(II) for Azide–Alkyne Cycloaddition and Cross‐Coupling Reactions

open access: yesEuropean Journal of Inorganic Chemistry, Volume 29, Issue 23, 13 August 2026.
An azide‐functionalized Cu(I)–NHC complex acts as both a monomer and a catalyst in an auto‐click polymerization, yielding a Cu(I)–NHC polymer that can be transmetalated to Pd(II). The two materials catalyze copper‐catalyzed azide–alkyne cycloaddition, C–N/C–O coupling, and Suzuki–Miyaura reactions, while copper reloading restores activity.
Cyril Nicolay   +6 more
wiley   +1 more source

Sonoenzymatically Triggered Cascading Degradation of Bioresorbable Materials for On‐Demand Transient Triboelectric Implants

open access: yesAdvanced Materials, Volume 38, Issue 45, 13 August 2026.
Our SEA strategy provides an efficient and biosafe approach for the on‐demand removal of implanted bioresorbable materials through cascading degradation that couples ultrasound‐triggered rapid mechanical disintegration with subsequent enzymatic degradation.
Jinsong Kim   +9 more
wiley   +1 more source

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

open access: yesAdvanced Science, Volume 13, Issue 43, 3 August 2026.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo   +7 more
wiley   +1 more source

Boosting the Photocatalytic Performance of Layered Double Hydroxides by In Situ Reactions with Metal Nanoclusters

open access: yesAggregate, Volume 7, Issue 8, August 2026.
An interfacial engineering strategy based on in situ reactions between metal nanoclusters and layered double hydroxides enables simultaneous nanocluster size regulation, heterojunction construction, and mesopore generation. The reconstructed interface enhances visible‐light harvesting, charge separation, and mass transport, providing a general strategy
Qi Chen   +5 more
wiley   +1 more source

Facile Use of Silver Nanoparticles-Loaded Alumina/Silica in Nanofluid Formulations for Enhanced Catalytic Performance toward 4-Nitrophenol Reduction. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Mannu R   +11 more
europepmc   +1 more source

Physiologically‐based pharmacokinetic modelling of uridine 5′‐diphosphoglucorosultransferase (UGT) substrate drugs in pregnant women

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2764-2776, August 2026.
Aims While pregnancy‐related changes in phase I enzyme activity are well‐documented, less is known about the impact on phase II enzymes. This study aimed to test the hypothesis that changes in the pharmacokinetics (PK) of uridine 5′‐diphosphoglucuronosyltransferase (UGT) substrates during pregnancy result from altered enzyme expression or activity ...
William Saffaf   +6 more
wiley   +1 more source

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