Results 161 to 170 of about 33,846 (277)

Antimicrobial photodynamic therapy in Candida spp. biofilms: In vitro and in vivo protocols

Photochemistry and Photobiology, EarlyView.
This review addresses the critical challenges in translating in vitro antimicrobial photodynamic therapy protocols to in vivo models, with a particular focus on the hurdles of standardization. The vast diversity in photosensitizers and light parameters across different target cells and models requires a rigorous optimization process.
Lívia Mara Alves Figueiredo‐Godoi, Ana Júlia Barbosa Tomé, Cristina Kurachi   +2 more
wiley   +1 more source

Immune platelet transfusion refractoriness associated with anti‐CD36 alloimmunisation in a Brazilian patient with platelet CD36 deficiency

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Immune platelet transfusion refractoriness (PTR) is usually mediated by anti‐HLA class I antibodies; immunisation against CD36 (platelet glycoprotein IV [GPIV]) is relatively rare. Platelet CD36 deficiency shows marked ethnic variability and is seldom reported in admixed Latin American populations.
Rayane Dayse Alves Conserva, Luiz Frederico Bezerra Honorato Junior, Ana Paula Hitomi Yokoyama, Thiago Henrique Costa, Luis Henrique Cardoso Fedeli, Ana Cynira Franco Marret, Eduardo Perez Bastos, Fabio Pires de Souza Santos, Luana Nobrega Costa, Livia Chiosini de Nadai, Carolina Bonet‐Bub, Jose Mauro Kutner   +11 more
wiley   +1 more source

Development and Characterization of Shikonin-Loaded NLC with Enhanced Photostability in Hydrogel-Based Dermal Patch. [PDF]

Pharmaceutics
Rueangpraphai K, Kiattisin K, Junmahasathien T.   +2 more
europepmc   +1 more source

Antioxidant supplementation blunts the proteome response to 3 weeks of sprint interval training preferentially in human type 2 muscle fibres

The Journal of Physiology, EarlyView.
Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma, Marta Murgia, Sigitas Kamandulis, Stefano Gastaldello, Marius Brazaitis, Audrius Snieckus, Nerijus Eimantas, Mati Pääsuke, Sebastian Edman, William Apro, Daniel C. Andersson, Håkan Westerblad, Tomas Venckunas   +12 more
wiley   +1 more source

TP53-Mutated Preneoplastic Colonies, Adaptive Immune Response, and Risk for Lung Cancer and COPD. [PDF]

Cancer Prev Res (Phila)
Willey JC, Boring AR, Crawford EL, Lei KN, Blomquist TM, Amos CI, Deppen SA, Grogan EL, Chen H, Omballi M, Craig DJ.   +10 more
europepmc   +1 more source

Heat tolerance of Mediterranean land snails under induced dormancy in South Australia

Annals of Applied Biology, Volume 190, Issue 1, January 2027.
Dry heat treatment of 60°C, for a minimum of 1 h, was shown to be an effective method to treat Cernuella virgata and Theba pisana land snails following periods of induced dormancy. The results from this project support the development of a scientifically based, environmentally friendly, safe phytosanitary treatment option to effectively control the ...
Lakshmi C. Nacey, Brian W. Garms, Jorgiane B. Parish, Judy Bellati, Nathan D. Luke, Peter Crisp   +5 more
wiley   +1 more source

Lipid matrix composition-tuned nanoparticles for enhanced topical retinol delivery and anti-photoaging efficacy. [PDF]

Int J Pharm X
Shin HK, Lee EY, Lee S, Min C, Yi M, Cho SY, Bok SH, Roh YH.   +7 more
europepmc   +1 more source

Implementation of Nano Flow Chromatography Coupled to Mass Spectrometry as a Reliable and Sensitive Discovery Lipidomics Platform

Rapid Communications in Mass Spectrometry, Volume 40, Issue 23, 15 December 2026.
ABSTRACT Rationale Untargeted lipidomics is commonly performed at analytical flow rates, which consume more solvent and may require higher on‐column sample loads when sensitivity is limited by analyte abundance. Nano flow separations use lower flow rates and sample loads, reducing solvent consumption and facilitating improved electrospray ionization ...
Ciara J. Sallowicz, Thiago Mattos, Rahul R. Deshpande, Bashar Amer, Susan S. Bird   +4 more
wiley   +1 more source

PEGylated gambogenic acid nanostructured lipid carriers enhance intracellular delivery in A549 cells via clathrin-, caveolae-mediated endocytosis and macropinocytosis. [PDF]

Am J Transl Res
Zhang B, Yu Q, Chang J, Chen W.
europepmc   +1 more source

Systems‐level phosphoproteomics reveals calcium/calmodulin‐dependent protein kinase kinase 2‐driven kinase signaling underlying malignant phenotypes in gastric cancer

Journal of Cell Communication and Signaling, Volume 20, Issue 4, December 2026.
CAMKK2 inhibition induces extensive phosphoproteomic remodeling associated with cell cycle regulation, RNA processing, and kinase signaling networks in gastric cancer. Integrated systems‐level analyses identified dysregulated CDK, SRPK, MAPK, and AKT signaling pathways underlying malignant phenotypes and highlighted CAMKK2 as a potential therapeutic ...
Mohd. Altaf Najar, T. S. Keshava Prasad, Prashant Kumar Modi   +2 more
wiley   +1 more source