Results 191 to 200 of about 33,846 (277)

Pathogenic Variants in HEPACAM Alter Protein Localization and Interactome in Astrocytes of the Developing Mouse Cortex

Glia, Volume 74, Issue 11, November 2026.
Pathogenic variants alter hepaCAM protein distribution. Astrocyte‐specific hepaCAM TurboID reveals KCNQ2 as a new interaction partner. Pathogenic variants alter hepaCAM association with key transmembrane proteins. ABSTRACT Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare leukodystrophy characterized by early‐onset macrocephaly,
Robert W. Lewis, Breana C. Dogan, Amy L. Stanek, Elliot B. Evans, Madelyn G. Coble, Hayli E. Spence‐Osorio, Karen L. G. Farizatto, Angie L. Mordant, C. Allie Mills, Laura E. Herring, Katherine T. Baldwin   +10 more
wiley   +1 more source

Novel lipid and ascorbyl stearate biomimetic vancomycin-loaded nanostructured lipid carrier therapy for bacterial infections and sepsis. [PDF]

RSC Adv
Nyandoro VO, Omolo CA, Ismail EA, Tageldin A, Gafar MA, Govender J, Govender T.   +6 more
europepmc   +1 more source

Impact of Dupilumab Therapy on Skin Barrier Function in Patients With Moderate‐to‐Severe Atopic Dermatitis: A Phase IV, Non‐Randomized, Open‐Label, Parallel‐Group Clinical Study

MedComm, Volume 7, Issue 11, November 2026.
This 16‑week study assessed impact of dupilumab on skin barrier function in patients with moderate‑to‑severe atopic dermatitis (AD). Tape‑stripped stratum corneum samples for multi‑omic profiling, alongside transepidermal water loss measurements, were collected from lesional/non‑lesional AD skin and healthy controls at seven time points.
Taoming Liu, Shuting Chen, Weijia Zhao, Dake Di, Jiao Liu, Yuyang Tian, Yurong Luo, Yingping Xu, Ruzeng Xue, Li Ye, Xiaoping Pei, Bihui Yu, Yu Wang, Jiao Zhang, Xiaoling Yu, Wei Wen, Liyan Yuan, Suyun Ji, Claire Hu, Dan Shen, Yiqing Guo, Yunsheng Liang   +21 more
wiley   +1 more source

Dietary curcumin encapsulated in nanostructured lipid carriers improves growth performance, feed utilization efficiency, and resistance to <em>Streptococcus agalactiae</em> in Nile tilapia (<em>Oreochromis niloticus</em>). [PDF]

Vet World
Kengkittipat W, Kamble MT, Kitiyodom S, Yostawonkul J, Sawatphakdee G, Thompson KD, Medhe SV, Jeamsripong S, Pirarat N.   +8 more
europepmc   +1 more source

Curcumin in the Treatment of Various Diseases: Mechanism of Action, Bioavailability, Therapeutic Effects, and Current Clinical Trials

MedComm, Volume 7, Issue 11, November 2026.
Curcumin, a naturally occurring polyphenol, exhibits significant anti‐inflammatory and antioxidant capabilities. This review elucidates the specific molecular mechanisms by which curcumin exerts therapeutic effects on various diseases, including neurological disorders, cardiovascular diseases, cancers, inflammatory disorders, and autoimmune diseases ...
Lin Wang, Qifei Pan, Wenjuan Long, Xinyao Li, Jianqin Mao, Sitong Zhou, Zihui Wang, Xuelian Zou, Yuqing She, Mingqin Shi, Yang Zhou, Jiarong Du, Zhongyang Hu, Xiaoman Lv, Yishu Chen, Dongdong Qin   +15 more
wiley   +1 more source

Recent advances in SLN and NLC-based lipid nanoparticles for cosmetic, dermal, and transdermal drug delivery: A comprehensive review. [PDF]

Bioimpacts
Kavathekar PK, Pawar PK.
europepmc   +1 more source

Identification of Potential Biomarkers for Ulcerative Colitis and Analysis of Immune Cell Infiltration: A Study Based on Data‐Independent Acquisition Proteomics and the GEO Public Database

PROTEOMICS – Clinical Applications, Volume 20, Issue 6, November 2026.
ABSTRACT Background Ulcerative colitis (UC) is a challenging inflammatory bowel disease characterized by chronic inflammation of the colon's mucosal layer. Despite advances in medical research, UC lacks definitive diagnostic tests and targeted treatments.
Shuai Wang, Hualiang Deng, Dajuan Sun
wiley   +1 more source

A novel approach for wound treatment using <i>Mitragyna speciosa</i>-encapsulated nanostructured lipid carriers in hydrogel film. [PDF]

J Adv Pharm Technol Res
Zulkifli AKI, Ashari SE, Ahmad S, Hassan M, Ali RM.   +4 more
europepmc   +1 more source

Architecting and Industrializing Advanced Production and Manufacturing Systems for Critical Industries

Systems Engineering, Volume 29, Issue 6, Page 1136-1151, November 2026.
ABSTRACT Advanced production systems play a vital role in modern society. Such systems are developed and industrialized over multiple years and at great expense. The complexities of these systems are exacerbated in the case of metal additive manufacturing, which involves numerous process variables and relies on various auxiliary systems.
Duncan W. Gibbons, Andre F. van der Merwe   +1 more
wiley   +1 more source

Hypocretin-1/orexin-A fragment1-16 as a potential surrogate marker for diagnosing narcolepsy type 1. [PDF]

Sleep
Wenz ES, Prost JC, Braga-Lagache S, Mäder GM, Warncke JD, Luginbühl M, Wuethrich PY, Lersch F, Schankin C, Filchenko I, Fregolente L, Zub K, iSPHYNCS consortium, Nishino S, Largiadèr CR, Heller M, Tafti M, Schmidt MH, Bassetti CLA.   +18 more
europepmc   +1 more source