Results 71 to 80 of about 33,846 (277)

Plants responding to natural land cover (NLC) at species-level and community-level.

open access: yes, 2021
a, The occurrence probability of 1 122 native plant species responding to NLC. Each grey line indicates one species, and the dark line means the average response of all 1 122 native species.
Kaixuan Pan (11714457)   +5 more
core   +1 more source

Low SLC8A1 in Colorectal Cancer Dictates Radiotherapy Resistance Through Calcium‐Dependent ANXA2+sEVs Driving M2 Polarization of TAMs

open access: yesAdvanced Science, EarlyView.
SLC8A1 deficiency in colorectal cancer cells increases intracellular calcium signaling, promoting the secretion of ANXA2‐enriched small extracellular vesicles. These vesicles reprogram tumor‐associated macrophages towards an M2 phenotype, which in turn fosters a tumor microenvironment conducive to radioresistance and is associated with poor patient ...
Yimin Fang   +18 more
wiley   +1 more source

Community Land Registration in Kenya, Tracing the Progress Towards Equity, Accountability, and Tenure Security

open access: yesAfrican Journal on Land Policy and Geospatial Sciences
Context and background Community Land Protection in Kenya gained traction with the enactment of the Community Land Act in 2016. The stakeholders, comprising state and non-state actors, have since made significant progress, registering 15% of community
Robert Koech   +3 more
doaj   +1 more source

Preferred NLC-F and NLC-O of native plant species, which are classified into rare and common species.

open access: yes, 2021
a, Two-dimensional plot indicating the preferred NLC-F and NLC-O of each species. Each dot indicates one species. Yellow dots indicate rare species and turquoise dots indicate common species. b, Number of dots within each subgroup along the x axis (0%, 0–
Kaixuan Pan (11714457)   +5 more
core   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

open access: yesAdvanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang   +9 more
wiley   +1 more source

Comparison of long-term Moscow and Danish NLC observations: statistical results

open access: yes, 2006
International audienceNoctilucent clouds (NLC) are the highest clouds in the Earth's atmosphere, observed close to the mesopause at 80?90 km altitudes.
Kirkwood, S.   +5 more
core   +1 more source

Multi‐Technique Integration Identifies O‐GlcNAc Transferase in Fibroblast‐Like Synoviocytes as a Therapeutic Target for Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie   +14 more
wiley   +1 more source

Preparation and Stability of Nanostructured Lipid Carriers of Phytosterols with Walnut Oil

open access: yesShipin gongye ke-ji, 2023
Nanostructured lipid carriers (NLC) for the encapsulation and protection of phytosterol (PS) were prepared using walnut oil as liquid lipid by high-pressure homogenization method.
Qitong HUAI   +8 more
doaj   +1 more source

Nrsn1–Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic‐phase Recovery After Ischemic Stroke

open access: yesAdvanced Science, EarlyView.
In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang   +18 more
wiley   +1 more source

Sustained-release genistein from nanostructured lipid carrier suppresses human lens epithelial cell growth [PDF]

open access: yesInternational Journal of Ophthalmology, 2016
AIM: To design and investigate the efficacy of a modified nanostructured lipid carrier loaded with genistein (Gen-NLC) to inhibit human lens epithelial cells (HLECs) proliferation. METHODS: Gen-NLC was made by melt emulsification method. The morphology,
Jin-Lu Liu   +6 more
doaj   +1 more source

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