Results 81 to 90 of about 33,846 (277)

Bone Marrow Macrophage STING Signaling is a Direct Nexus Linking Marrow Adipose Expansion to NAD+ Depletion and Osteogenic Decline in Skeletal Aging

Advanced Science, EarlyView.
This study reveals that during skeletal aging, bone marrow adipocyte‐derived sDPP4 primes STING signaling in macrophages. In combination with mitochondrial DNA, this signaling activates CD38 and depletes local NAD+/NMN, thereby impairing osteogenesis.
Zhichao Li, Kuanhui Gao, Mengjie Wang, Songlin Liang, Dandan Li, Guoqing Tan, Haipeng Xue, Yujie Liu, Peng Zhang, Zhanwang Xu, Wenxiang Cheng, Yongjun Wang, Nianhu Li   +12 more
wiley   +1 more source

Results on NLC grammars with one-letter terminal alphabets

, 1990
Node-label controlled graph grammars (NLC grammars) are a mechanism to generate sets of graphs (called graph languages). This paper examines the generating power of NLC grammars with a restricted connection relation and some closure properties of the ...
Hoffmann, Jochen, Main, Michael G.
core   +1 more source

Preferred NLC-F and NLC-O of native plant species, which are classified into threatened and not threatened species.

, 2021
a, Two-dimensional plot indicating the preferred NLC-F and NLC-O of each species. Each dot indicates one species. Red dots indicate threatened species and blue dots indicate not threatened species. b, Number of dots within each subgroup along the x axis (
Kaixuan Pan (11714457), Geert R. de Snoo (11714466), Koos Biesmeijer (752575), Ellen Cieraad (6471002), Merijn Moens (11714460), Leon Marshall (11714463)   +5 more
core   +1 more source

An Unbiased Geometry‐Resolved Membrane Platform for Proteome‐Scale Discovery of Membrane Curvature Sensors

Advanced Science, EarlyView.
A novel geometry‐resolved membrane platform provides a seamlessly integrated pipeline for studying curvature‐sensing proteins. By linking shotgun proteomics with quantitative imaging, this approach enables both the unbiased discovery and rigorous validation of novel sensors across the entire curvature range—positive, negative, and zero.
Takumi Komikawa, Rikuto Kawakami, Kunanon Chattrairat, Tatsuya Niwa, Taiga Ajiri, Takao Yasui, Masayoshi Tanaka   +6 more
wiley   +1 more source

AnomalousZ′ effects in the WW channel at NLC [PDF]

Zeitschrift für Physik C: Particles and Fields, 1996
We consider the virtual signals of a $Z'$ of very general type in the process $e^+e^-\to W^+W^-$ at a future linear collider (NLC). We show that possible deviations from the SM predictions in this channel are related to similar deviations in the purely leptonic one in a way that is only characteristic of this $Z'$ model, and not in general of possible ...
Chiappetta, P., Renard, F. M., Verzegnassi, C.   +2 more
openaire   +2 more sources

SAV1 in Cooperation With FKBP52 Participates in Implantation

Advanced Science, EarlyView.
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao, Yafang Lu, Zhaoyu Jia, Junxiang Ren, Ziyi Ge, Xinyu Liu, Hui Zhao, Zi‐Jiang Chen, Junhao Yan, Wei Wang, Jia Yuan   +10 more
wiley   +1 more source

Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2

Advanced Science, EarlyView.
Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang, Chuanzan Zhou, Jiaoyan He, Pengpeng Huang, Rong Zhang, Huan Hu, Meng Jiao, Linyi Hu, Feng Liu, Xiaolong Qi, Xiang He, Yunkai Yang, Y Eugene Chinn, Dechao Feng, Dahong Zhang, Qi Zhang   +15 more
wiley   +1 more source

Supersymmetry at LHC and NLC [PDF]

Nuclear Physics B - Proceedings Supplements, 1998
This talk discusses the prospects for supersymmetry studies at the LHC and NLC. The results are based on those of the Supersymmetry Working Group at the 1996 Snowmass Workshop.
openaire   +2 more sources

Enhanced Regular Perturbation-Based Nonlinearity Compensation Technique for Optical Transmission Systems

IEEE Photonics Journal, 2019
The regular perturbation (RP) series used to analytically approximate the solution of the nonlinear Schrodinger equation has a serious energy-divergence problem when truncated to the first order.
O. S. Sunish Kumar, Abdelkerim Amari, Octavia A. Dobre, Ramachandran Venkatesan   +3 more
doaj   +1 more source

SCTR–Expressing Astrocyte–Serotonergic Neuron Signaling Drives Sexual Dimorphism in Depression Through KAT7/H4ac–Foxc2 Epigenetic Axis in an AMPK‐Dependent Manner

Advanced Science, EarlyView.
Astrocytic SCTR modulates depressive‐related phenotypes via AMPKα1, whereas lowered Mt1 blunts Megalin‐dependent AMPKα2 signaling in serotonergic neurons. Diminished AMPKα2 hinders KAT7 nuclear translocation, curtails KAT7 occupancy and H4K8ac at the Foxc2 promoter, and represses Foxc2 transcription, revealing cell‐type‐specific AMPK‐linked epigenetic ...
Fantao Meng, Jing Liu, Juanjuan Dai, Min Wu, Wentao Wang, Mengdi Zhang, Shujun Jiang, Yifan Cao, Lihong Xu, Lin Du, Dan Wang, Di Zhao, Gaofeng Qin, Dong Wang, Wei Li, Chen Li   +15 more
wiley   +1 more source