Results 121 to 130 of about 7,196 (266)
Formulation and physicochemical characterization of nanostructured lipid carriers (NLCS) loaded with Ibuprofen [PDF]
Objective: This study aimed to develop and characterize na- nostructured lipid carriers (NLCs) loaded with 1% ibuprofen (IBU-NLC) to enhance skin penetration and enable localized treatment of inflammatory musculoskeletal conditions, such as ...
Costa, Paulo +3 more
core +2 more sources
MoleculesThe continuous synthesis of nanoparticles (NPs) has been actively studied due to its great potential to produce NPs with reproducible and controllable physicochemical properties.
Hyeon Su Lim, Won Il Choi, Jong-Min Lim
doaj +1 more source
Plant‐Derived Natural Product Nanodelivery System in Cancer Therapy
Phytotherapy Research, EarlyView.This review comprehensively summarizes the recent progress and emerging concepts in nanotechnology‐based delivery systems for plant‐derived natural products, with a particular focus on their application in precision cancer therapy. ABSTRACT Plant‐derived natural products have emerged as important sources of anticancer agents because of their diverse ...
Changqi Shi +9 more
wiley +1 more source
Journal of Applied Pharmaceutical ResearchBackground: Glioblastoma multiforme is a highly invasive and aggressive brain cancer, with limited therapy options mostly due to the restrictive properties of the blood-brain barrier (BBB).
Yogita Ale +3 more
doaj +1 more source
Phytotherapy Research, EarlyView.Proposed mechanism by which notoginsenoside R2 (NGR2) attenuates renal interstitial fibrosis. In injured renal tubular epithelial cells, CASP2 downregulation and enhanced ubiquitin‐dependent degradation of ALDH3A1 disrupt mitochondria‐associated endoplasmic reticulum membranes (MAMs) and impair fatty acid oxidation (FAO), leading to lipid accumulation ...
Guanting Chen +10 more
wiley +1 more source
Nanostructured Lipid Carriers (NLCs) for Cancer Therapy via Pulmonary Drug Delivery
Lung cancer has been a leading cause of cancer-related deaths worldwide over the past years, creating the necessity for novel therapeutic approaches that can enhance drug delivery efficiency while minimising systemic toxicity.
Apostolou, M
core
Oral Delivery of Semaglutide via Nanostructured Lipid Carriers (NLCs): A Review of Formulation, Stability, and Intestinal Uptake [PDF]
Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has demonstrated significant efficacy in obesity management. However, its therapeutic potential is limited by poor oral bioavailability and enzymatic degradation in the gastrointestinal ...
Amisha Praja, Neha Deshwal, Swati Raturi
core +1 more source
Phytotherapy Research, EarlyView.ABSTRACT Rheumatoid arthritis (RA) is an autoimmune condition marked by joint inflammation, cartilage destruction, and bone damage. Conventional treatments, including NSAIDs and DMARDs, have shown effectiveness in slowing down disease progression, but prolonged exposure to such medications results in adverse effects and lack of tolerance among patients.
Yogesh Khairnar +5 more
wiley +1 more source
Responsive Materials, EarlyView.Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan +8 more
wiley +1 more source
SLNs and NLCs for Skin Applications: Enhancing the Bioavailability of Natural Bioactives
Natural bioactives are mixtures of compounds extracted from plants with physicochemical properties that are usually not favorable for penetrating the skin’s complex barrier.
Mirela-Liliana Moldovan +2 more
core +1 more source