Results 91 to 100 of about 192,001 (267)

The critical impact of remote pilot modelling in evaluation of detect-and-avoid systems explained for ACAS Xu

open access: yesEuropean Journal of Transport and Infrastructure Research
Detect-and-avoid (DAA) systems for remotely piloted aircraft systems (RPAS) can provide remain well clear (RWC) guidance as well as shorter term resolution advisories (RAs) for collision avoidance, which are both provided in the vertical and horizontal ...
Sybert Stroeve   +2 more
doaj   +1 more source

Early and High‐Dose Glucocorticoid Use and Survival in Advanced NSCLC Receiving Immune Checkpoint Inhibitors: A Multicenter Target Trial Emulation

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Despite the immunomodulatory mechanism of immune checkpoint inhibitors (ICIs), systemic glucocorticoids are commonly used in advanced non–small cell lung cancer (NSCLC). Evidence regarding their effects on ICI outcomes is inconsistent, in part due to confounding by indication and immortal time bias.
Da Eun Lee   +13 more
wiley   +1 more source

Long‐term cardiovascular outcomes of immune checkpoint inhibitor‐related myocarditis: A large single‐centre analysis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1237-1245, April 2025.
Abstract Aims Immune checkpoint inhibitors (ICI) are the cornerstone of modern oncology; however, side effects such as ICI‐related myocarditis (irM) can be fatal. Recently, Bonaca proposed criteria for irM; however, it is unknown if they correlate well with cardiovascular (CV) ICI‐related adverse events.
Lorenzo Braghieri   +12 more
wiley   +1 more source

Neutrophil-to-Lymphocyte Ratio Predicts Clinical Outcome of Severe Acute Exacerbation of COPD in Frequent Exacerbators

open access: yesInternational Journal of COPD, 2021
Fang-Ying Lu,1,2,* Rong Chen,1,2,* Ning Li,1,2 Xian-Wen Sun,1,2 Min Zhou,1,2 Qing-Yun Li,1,2 Yi Guo1,2 1Department of Respiratory and Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s ...
Lu FY   +6 more
doaj  

Serum methylmalonic acid levels and epilepsy prevalence: Association analysis, exploratory mediation, and clinical corroboration

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective This study aimed to investigate the association between methylmalonic acid (MMA) and epilepsy prevalence and to explore potential inflammatory and nutritional pathways underlying this association. Methods This study included adults aged ≥ 20 years from the National Health and Nutrition Examination Survey (NHANES) 2011–2014.
Ningyu Wei   +5 more
wiley   +1 more source

The neutrophil to lymphocyte ratio in heart failure: a comprehensive review

open access: yesRomanian Journal of Internal Medicine, 2019
Introduction. Heart failure (HF) and systemic inflammation are interdependent processes that continuously potentiate each other. Distinct pathophysiological pathways are activated, resulting in increased neutrophil count and reduced lymphocyte numbers ...
Delcea Caterina   +2 more
doaj   +1 more source

Centralized Landing Flow Merging for Drones Using Deep Reinforcement Learning

open access: yesAerospace
Drones are expected to support applications such as emergency response, parcel delivery, and infrastructure monitoring in dense urban airspaces, creating traffic levels that are unmanageable for human operators.
Sasha Vlaskin   +5 more
doaj   +1 more source

HPV Serology and Circulating Viral DNA for Detection, Genotyping, and Measurement of Disease Burden in Oropharyngeal Cancer

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT The incidence of human papillomavirus‐positive (HPV+) oropharyngeal cancer (OPC) has increased rapidly, and HPV early antigen serology has been proposed as a scalable and cost‐effective early detection test. HPV seropositivity can precede clinical presentation of OPC by several years, so additional surveillance procedures may be necessary to ...
Lucas Penny   +23 more
wiley   +1 more source

The plant microbiome: From ecological foundations to precision microbial engineering for sustainable agriculture

open access: yesiMeta, EarlyView.
From ecological principles to precision engineering of plant microbiomes for sustainable agriculture. The plant holobiont integrates diverse microbial niches (including rhizosphere, endosphere, phyllosphere, seed, and aerial‐root mucilagesphere), host genetics (namely M genes), and host metabolites. Furthermore, molecular dialogues, including rhizobial
Mi Wei   +26 more
wiley   +1 more source

Correlation Between IL-8, C-Reactive Proteins (CRP) and Neutrophil to Lymphocyte Ratio (NLR) as Predictor of Mortality in COVID-19 Patients with Diabetes Mellitus Comorbidity

open access: yesInternational Journal of General Medicine, 2023
Agustin Iskandar,1– 3 Dearikha K Mayashinta,2,3 Robert Robert,3 Nur Samsu,4 Agustina Tri Endharti,2 Edy Widjajanto3 1Doctoral Program in Medical Science, Faculty of Medicine, Universitas Brawijaya/Saiful Anwar General Hospital, Malang, Indonesia ...
Iskandar A   +5 more
doaj  

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