Results 291 to 300 of about 8,284,629 (305)

NACHT-LRR proteins (NLRs) in bacterial infection and immunity

Trends in Microbiology, 2005
Eukaryotes have evolved systems to detect bacterial intrusion. Recognition of bacteria relies on the sensing of pathogen associated molecular patterns (PAMPs) by host pattern recognition molecules (PRMs), which include various families of leucine-rich repeat (LRR) bearing proteins in plants and animals.
Thomas A, Kufer, Jörg H, Fritz, Dana J, Philpott   +2 more
openaire   +2 more sources

Cytofluorometric Quantification of Cell Death Elicited by NLR Proteins

2016
Nucleotide-binding domain and leucine-rich repeat containing (NLR) proteins, also known as NOD-like receptors, are critical components of the molecular machinery that senses intracellular danger signals to initiate an innate immune response against invading pathogens or endogenous sources of hazard. The best characterized effect of NLR signaling is the
Valentina, Sica, Gwenola, Manic, Guido, Kroemer, Ilio, Vitale, Lorenzo, Galluzzi   +4 more
openaire   +2 more sources

NLRs: Nucleotide-Binding Domain and Leucine-Rich-Repeat-Containing Proteins

EcoSal Plus, 2009
Eukaryotes have evolved strategies to detect microbial intrusion and instruct immune responses to limit damage from infection. Recognition of microbes and cellular damage relies on the detection of microbe-associated molecular patterns (MAMPs, also called PAMPS, or pathogen-associated molecular patterns) and so-called "danger signals" by ...
Leticia A M, Carneiro, J Örg H, Fritz, Thomas A, Kufer, Leonardo H, Travassos, Szilvia, Benko, Dana J, Philpott   +5 more
openaire   +2 more sources

Tsw: an NLR protein that keeps viruses away

Plant Cell Reports, 2023
Priya Gahlowt, Durgesh Kumar Tripathi, Ravi Gupta, Vijay Pratap Singh   +3 more
openaire   +2 more sources

Characterization of the human NLR protein NLRC5 [PDF]

, 2013
Nucleotide-binding domain, leucine-rich repeat (NLR)-containing proteins play important roles in the innate immune system as intracellular pattern recognition receptors. The most prominent members, NOD1, NOD2 and NLRP3 have been extensively shown to trigger NF-kB activation or IL-1b/IL-18 processing upon pathogen infection, respectively.
openaire  

A wheat tandem kinase and NLR pair confers resistance to multiple fungal pathogens.

Science
Tandem kinase proteins underlie the innate immune systems of cereal plants, but how they initiate plant immune responses remains unclear. This report identifies wheat protein wheat tandem NBD 1 (WTN1), a noncanonical nucleotide-binding leucine-rich ...
P. Lu, Gaohua Zhang, Jing Li, Zhen Gong, Gao-Jie Wang, Ling-Li Dong, Huai-Zhi Zhang, Guanghao Guo, M. Su, Ke Wang, Yue-Ming Wang, K. Zhu, Qiu-Hong Wu, Yong-Xing Chen, Miaomiao Li, Baoge Huang, Beibei Li, Wenling Li, Lei Dong, Yikun Hou, Xuejia Cui, Hongkui Fu, Dan Qiu, Chengguo Yuan, Hongjie Li, Jian-Min Zhou, Guan-Zhu Han, Yu-Hang Chen, Zhi-Yong Liu   +28 more
semanticscholar   +1 more source

Balanced plant helper NLR activation by a modified host protein complex

Nature
Nucleotide-binding leucine-rich repeat (NLR) receptors play crucial roles in plant immunity by sensing pathogen effectors1. In Arabidopsis, certain sensor NLRs function as NADases to catalyse the production of second messengers2,3, which can be recognized by enhanced disease susceptibility 1 (EDS1) with its partner senescence-associated gene 101 ...
Shijia Huang, Junli Wang, Ridan Song, Aolin Jia, Yu Xiao, Yue Sun, Lin Wang, Dennis Mahr, Zhongshou Wu, Zhifu Han, Xin Li, Jane E. Parker, Jijie Chai   +12 more
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TaANK-TPR1 enhances wheat resistance against stripe rust via controlling gene expression and protein activity of NLR protein TaRPP13L1.

Developmental Cell
Nucleotide-binding site, leucine-rich repeat (NLR) proteins activate a robust immune response on recognition of pathogen invasion. However, the function and regulatory mechanisms of NLRs during Puccinia striiformis f. sp. tritici (Pst) infection in wheat
Shuangyuan Guo, Feng Zhang, Xiaoya Du, Xin-Mei Zhang, Xue-Ling Huang, Zelong Li, Yanqin Zhang, Pengfei Gan, Huankun Li, Min Li, Xin-Yu Wang, Chunlei Tang, Xiao-Jie Wang, Zhen-Sheng Kang, Xin-Mei Zhang   +14 more
semanticscholar   +1 more source

Activation of a helper NLR by plant and bacterial TIR immune signaling.

Science
Plant intracellular nucleotide-binding leucine-rich repeat (NLR) receptors with an N-terminal Toll/interleukin-1 receptor (TIR) domain sense pathogen effectors to initiate immune signaling.
Hua Yu, Wei-Ying Xu, Si-Si Chen, Xiao-Xian Wu, Wei-Wei Rao, Xiaoxiao Liu, Xiao-Yan Xu, Jingqi Chen, Marc T. Nishimura, Yu Zhang, Li Wan   +10 more
semanticscholar   +1 more source

Update on the domain architectures of NLRs and R proteins

Biochemical and Biophysical Research Communications, 2006
Albrecht, M., Takken, F.L.W.
openaire   +4 more sources