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Predictive Value of EGFR Expression for the Efficacy of Near-Infrared Photoimmunotherapy in Head and Neck Cancer. [PDF]
Suzuki S +9 more
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Molecular mechanisms of plant NLR activation and signalling. [PDF]
Maruta N +3 more
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Advances in Nod-like receptors (NLR) biology
Cytokine & Growth Factor Reviews, 2014The innate immune system is composed of a wide repertoire of conserved pattern recognition receptors (PRRs) able to trigger inflammation and host defense mechanisms in response to endogenous or exogenous pathogenic insults. Among these, nucleotide-binding and oligomerization domain (NOD)-like receptors (NLRs) are intracellular sentinels of cytosolic ...
François, Barbé +2 more
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A nucleocytoplasmic-localized E3 ligase affects the NLR receptor stability
Biochemical and Biophysical Research Communications, 2021Ubiquitination is a pivotal post-translational modification that regulates turnover of nucleotide-binding site and leucine-rich repeat receptors (NLRs). As a RING-type E3 ligase, BOI (Botrytis susceptible1 interactor) has been reported to interact with different proteins, and function in the nucleus.
Jianzhong Huang, Xiaoqiu Wu, Zhiyong Gao
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NLR surveillance of pathogen interference with hormone receptors induces immunity
Nature, 2022Phytohormone signalling pathways have an important role in defence against pathogens mediated by cell-surface pattern recognition receptors and intracellular nucleotide-binding leucine-rich repeat class immune receptors1,2 (NLR). Pathogens have evolved counter-defence strategies to manipulate phytohormone signalling pathways to dampen immunity and ...
Jing Chen +17 more
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Toll-like receptors (TLRs) and Nod-like receptors (NLRs) in inflammatory disorders
Seminars in Immunology, 2009Toll-like receptors (TLRs) and Nod-like receptors (NLRs) are two major forms of innate immune sensors, which provide immediate responses against pathogenic invasion or tissue injury. Activation of these sensors induces the recruitment of innate immune cells such as macrophages and neutrophils, initiates tissue repair processes, and results in adaptive ...
Masayuki, Fukata +2 more
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