Results 121 to 130 of about 82,639 (162)

Predictive Value of EGFR Expression for the Efficacy of Near-Infrared Photoimmunotherapy in Head and Neck Cancer. [PDF]

open access: yesJMA J
Suzuki S   +9 more
europepmc   +1 more source

Advances in Nod-like receptors (NLR) biology

Cytokine & Growth Factor Reviews, 2014
The innate immune system is composed of a wide repertoire of conserved pattern recognition receptors (PRRs) able to trigger inflammation and host defense mechanisms in response to endogenous or exogenous pathogenic insults. Among these, nucleotide-binding and oligomerization domain (NOD)-like receptors (NLRs) are intracellular sentinels of cytosolic ...
François, BarbĂ©   +2 more
openaire   +2 more sources

A nucleocytoplasmic-localized E3 ligase affects the NLR receptor stability

Biochemical and Biophysical Research Communications, 2021
Ubiquitination is a pivotal post-translational modification that regulates turnover of nucleotide-binding site and leucine-rich repeat receptors (NLRs). As a RING-type E3 ligase, BOI (Botrytis susceptible1 interactor) has been reported to interact with different proteins, and function in the nucleus.
Jianzhong Huang, Xiaoqiu Wu, Zhiyong Gao
openaire   +2 more sources

NLR surveillance of pathogen interference with hormone receptors induces immunity

Nature, 2022
Phytohormone signalling pathways have an important role in defence against pathogens mediated by cell-surface pattern recognition receptors and intracellular nucleotide-binding leucine-rich repeat class immune receptors1,2 (NLR). Pathogens have evolved counter-defence strategies to manipulate phytohormone signalling pathways to dampen immunity and ...
Jing Chen   +17 more
openaire   +2 more sources

Toll-like receptors (TLRs) and Nod-like receptors (NLRs) in inflammatory disorders

Seminars in Immunology, 2009
Toll-like receptors (TLRs) and Nod-like receptors (NLRs) are two major forms of innate immune sensors, which provide immediate responses against pathogenic invasion or tissue injury. Activation of these sensors induces the recruitment of innate immune cells such as macrophages and neutrophils, initiates tissue repair processes, and results in adaptive ...
Masayuki, Fukata   +2 more
openaire   +2 more sources

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