Results 121 to 130 of about 1,342,871 (301)

Development and External Validation of a Postoperative Risk Score for Venous Thromboembolism in Epithelial Ovarian Cancer

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, is a major complication in women with epithelial ovarian cancer (EOC). We aimed to develop and externally validate an early postoperative risk score to identify EOC patients at increased risk of VTE after debulking surgery.
Qiu‐Lin Cui   +6 more
wiley   +1 more source

Risk Factors Influencing Efficacy and Prognosis Evaluation of Neoadjuvant Systemic Therapy in Triple‐Positive Breast Cancer

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT To identify the determinants of the response to neoadjuvant systemic therapy (NST) in triple‐positive breast cancer (TPBC), we retrospectively enrolled 520 patients with human epidermal growth factor receptor 2 (HER2)‐positive breast cancer who were treated at The First Affiliated Hospital of Chongqing Medical University between January 2015 ...
Lin‐Rui Miao   +7 more
wiley   +1 more source

NETosis in the Kidney, Liver, and Lung of Mice With Cecal Ligation and Puncture‐Induced Sepsis and the Ameliorating Effects of Adipose‐Derived Stem Cell Exosomes

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sepsis‐induced organ failure involves dysregulated neutrophil responses, including neutrophil extracellular trap (NET) formation, via NETosis. Exosomes generated from adipose‐derived stem cells (ADSCs) have shown potential in sepsis treatment. This study characterized organ‐specific NETosis in the kidney, liver, and lungs using a murine cecal ...
Shao‐Chun Wu   +5 more
wiley   +1 more source

Functional analysis of NLR type immune receptors in rice

open access: yes, 2022
Plant nucleotide-binding and leucine-rich repeat domain proteins (NLRs) are the most important class of pathogen resistance proteins in plants and have a primary role in sustainable plant health management. They act as immune sensors that recognize pathogen virulence factors named effectors that pathogens secrete during infection to promote disease ...
openaire   +1 more source

Responsiveness and ceiling effects of Knee Injury and Osteoarthritis Outcome Score following anterior cruciate ligament reconstruction: Evidence from the UK National Ligament Registry

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Multiple versions of the Knee Injury and Osteoarthritis Outcome Score (KOOS) are used in anterior cruciate ligament (ACL) populations, but their responsiveness and ceiling effects remain uncertain. This study aimed to evaluate the floor and ceiling effects, responsiveness and minimal important difference (MID) using the United Kingdom ...
Henry K. C. Searle   +9 more
wiley   +1 more source

Depth of Invasion Predicts Vocal Fold Motility and Muscle Invasion in Glottic Carcinoma

open access: yesThe Laryngoscope, EarlyView.
To determine whether depth of invasion (DOI) provides an objective surrogate for vocal fold motility and vocal muscle invasion in glottic squamous cell carcinoma. Methods and Results: In derivation and external validation cohorts, radiologic DOI strongly correlated with pathologic DOI and accurately predicted altered vocal fold motility and muscle ...
Elisa Bellini   +22 more
wiley   +1 more source

Striatal Dopaminergic Reserve Shapes the Longitudinal Impact of Peripheral Immune Activation on Motor Progression in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Peripheral immune dysregulation has been implicated in Parkinson's disease (PD) progression, but whether motor deterioration reflects accelerated nigrostriatal degeneration or residual dopaminergic reserve remains unclear. Objectives To examine whether baseline and time‐varying neutrophil‐to‐lymphocyte ratio (NLR) relate to motor ...
Osman Kahveci, Ulaş Ay, Tamer Demiralp
wiley   +1 more source

Deciphering plant–pathogen interaction with single‐cell omics

open access: yesNew Plant Protection, EarlyView.
Recent advances in single‐cell omics have enabled the decoding of gene regulatory networks at the cellular resolution during pathogen challenge. This review summarizes the technological developments in plant single‐cell omics and highlights their unique advantages for dissecting nearly all stages of plant–pathogen interactions, including initial ...
Lu Gan   +3 more
wiley   +1 more source

The epigenetic landscape of plant defense: Unlocking nature's toolkit for new plant protection

open access: yesNew Plant Protection, EarlyView.
This review examines how epigenetic mechanisms regulate plant immune gene activation, repression, and priming, then links these natural regulatory layers to emerging epigenetic editing, discussing their potential for precise, heritable crop protection and the challenges.
Xuexia Liu, Zhenhui Zhong
wiley   +1 more source

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