Results 161 to 170 of about 98,851 (337)

Association of inflammatory blood markers and pathological complete response in HER2-positive breast cancer: a retrospective single-center cohort study

open access: yesFrontiers in Immunology
IntroductionThe association between inflammatory blood markers (IBMs) (monocyte-to-lymphocyte ratio [MLR], neutrophil-to-lymphocyte ratio [NLR], and platelet-to-lymphocyte ratio [PLR]) and breast cancer has been extensively studied.
Xiaobin Chen   +41 more
doaj   +1 more source

Plasma Proteomics Analysis Identifying IGFBP2 as a Potential Diagnostic Biomarker for Laryngeal Squamous Cell Carcinoma

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Currently, there are no blood biomarkers available for the early diagnosis of laryngeal squamous cell carcinoma (LSCC). The objective of this study was to search for potential plasma biomarkers for the diagnosis of LSCC. Methods Plasma samples were taken from patients with LSCC and healthy controls for proteomic analysis.
Shuang Teng   +13 more
wiley   +1 more source

Impact of Social Grooming on Age‐Related Immune Health in Captive Baboons

open access: yesZoo Biology, EarlyView.
ABSTRACT Primate social behaviors are known to mitigate a number of negative psychological and physiological problems. Social connectedness in wild baboons can predict longevity and health, but the relationship between social grooming and physical health in captive baboons is less known.
Sara J. Cotton, Frances J. White
wiley   +1 more source

The Piks allele of the NLR immune receptor Pik breaks the recognition of AvrPik effectors of rice blast fungus

open access: hybrid, 2022
Gui Xiao   +12 more
openalex   +1 more source

Prognostic Significance of the Modified Glasgow Prognostic Score in Patients With Stage IV Melanoma Receiving Immune Checkpoint Inhibitors: A Single‐Center Retrospective Study

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape for malignant melanoma (MM). However, given variable response rates and potential toxicities, identifying robust biomarkers is crucial. We investigated whether the modified Glasgow Prognostic Score (mGPS) predicts treatment efficacy and toxicity in Asian patients with
Ken Horisaki   +4 more
wiley   +1 more source

Russian wheat aphid: a model for genomic plasticity and a challenge to breeders

open access: yesInsect Science, EarlyView.
Invasive foundress finds suitable habitat and reproduces through pathogenesis. Wingless females produce life offspring quickly, which leads to high population densities. High population densities result in competition, which may induce epigenetic changes and wing development for dispersal.
Astrid Jankielsohn   +8 more
wiley   +1 more source

Agitación de emergencia en operaciones de rinoplastia abierta: cocientes neutrófilos/ linfocitos y plaquetas/linfocitos como marcadores predictivos

open access: yesCirugía y Cirujanos
Objetivo: Evaluar la relación entre la agitación de emergencia y los cocientes preoperatorios neutrófilos/linfocitos (NLR) y plaquetas/linfocitos (PLR) tras una rinoplastia.
Yasir İlyas   +3 more
doaj   +1 more source

Type I and II Interferons Drive Abacavir Hypersensitivity via Treg Suppression and T‐Cell Enhancement in Immunocompetent HLA‐Transgenic Mice

open access: yesAllergy, EarlyView.
Upregulated HLA‐B*57:01 expression in Tg/KO mice amplifies abacavir‐specific CD8+ T‐cell activation, driven by enhanced antigen presentation. Abacavir treatment induces robust pDC expansion and IFN‐α production, which selectively suppresses memory Treg populations.
SuJin Hwang   +8 more
wiley   +1 more source

Functional analysis of NLR type immune receptors in rice

open access: yes, 2022
Plant nucleotide-binding and leucine-rich repeat domain proteins (NLRs) are the most important class of pathogen resistance proteins in plants and have a primary role in sustainable plant health management. They act as immune sensors that recognize pathogen virulence factors named effectors that pathogens secrete during infection to promote disease ...
openaire   +1 more source

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