Results 181 to 190 of about 61,577 (309)

College Loans and Human Capital Investment

International Economic Review, EarlyView.
ABSTRACT College loans facilitate access to education, but the repayment burden may distort posteducation human capital investment. We examine the role of college loans and loan repayment policies through a structural model of individuals' dynamic decisions on borrowing/saving, labor supply, and costly human capital investment. We estimate two versions
Chao Fu, Hsuan‐Chih (Luke) Lin, Atsuko Tanaka   +2 more
wiley   +1 more source

Nevus Lipomatosus Superficialis with Mixed Morphologic Features: Gross, Sonographic, and Histopathologic Correlation. [PDF]

Life (Basel)
Nguyen MT, Wu LP, Pham GM.
europepmc   +1 more source

Engineered NLS-Chimera Downregulates Expression of Aggregation-Prone Endogenous FUS

Importin β-superfamily nuclear import receptors (NIRs) mitigate mislocalization and aggregation of RNA-binding proteins (RBPs), like FUS and TDP-43, which are implicated in neurodegenerative diseases.
Girdhar, Amandeep, Cingolani, Gino, DePierro, Jacquelyn, Bajaj, Aditya, Buchler, Joseph R., Hayashi, Miyuki, Arunprakash, Nikhita, Kim, Kevin, Guo, Lin, Ko, Ying-Hui   +9 more
core  

Lake sturgeon (Acipenser fulvescens) growth and longevity estimated from adult capture–mark–recapture data

Journal of Fish Biology, EarlyView.
Abstract Effective fishery management policy depends on accurate life‐history data, particularly for harvested species. Longevity is a core life‐history trait that is directly related to annual survival and lifetime reproductive potential, but fish longevity is generally not well documented, particularly for long‐lived species.
Edward A. Baker, Scott F. Colborne, Nancy A. Auer, Kim T. Scribner, Douglas L. Larson, Andrew S. Briggs, Ronald M. Bruch, Margaret H. Stadig, Michael C. Donofrio   +8 more
wiley   +1 more source

Engineered NLS-PBase system boosts stability and productivity in recombinant cell lines. [PDF]

Bioresour Bioprocess
Zhou Y, Tian Y, Ran Q, Ye Q, Tan WS.
europepmc   +1 more source

Coupling of both a transactivation module and a double‐stranded DNA‐binding domain boosts Cas12i3 variant‐based cytosine and adenine editing in plants

Journal of Integrative Plant Biology, EarlyView.
Fusions of a transactivation module and a double‐stranded DNA‐binding domain produced effective Cas12i3 variant‐based cytosine and adenine base editors, with improved C‐to‐T and A‐to‐G base editing efficiency and expanded editing window. Generated herbicide‐resistant rice germplasm by using these base editors demonstrates their potential for precise ...
Chen Zhang, Jingying Li, Yucai Li, Lei Yan, Christina Seok Yien Yong, Shaoya Li, Yubing He, Lanqin Xia   +7 more
wiley   +1 more source

Unveiling nuclear localization signals in human arginine deiminase proteins. [PDF]

Protein Sci
Neira JL, Abian O, Velazquez-Campoy A, Rizzuti B.   +3 more
europepmc   +1 more source

Where is the NLS in Tip60?

, 2017
Tip60 is a lysine acetyltransferase (KAT), coded by the KAT5 gene, which is involved in transcription, DNA repair, and apoptosis. It acetylates histones, the ATM protein kinase, and the p53 tumor suppressor, among other targets, making it a key regulator
Vashishtha, Himali
core  

Enhanced exonuclease–Cas9 systems promote multiple nucleotide deletions with higher efficiency and broader targeting scope in plants

Journal of Integrative Plant Biology, EarlyView.
Cas9 preferentially generates small indels. By tethering an exonuclease and a DNA‐binding domain (DBD) to Cas9, the Exo‐DBD‐Cas9 system efficiently promotes multiple nucleotide deletions. These expanded deletions enable effective disruption of miRNA‐mediated regulation and relieve translational repression through targeted editing of 3′ untranslated ...
Rui Zhang, Xu Tang, Yao He, Wei Wang, Qiurong Ren, Yiping Qi, Yong Zhang   +6 more
wiley   +1 more source

Nuclear translocation of mitochondrial ferredoxin reductase is regulated by AKT-mediated phosphorylation. [PDF]

Biochem J
Nakajima KI, Mohibi S, Chen X, Zhang J.
europepmc   +1 more source