Results 41 to 50 of about 297,128 (308)
Frontiers in Plant Science, 2015 Compound identification is a major bottleneck in metabolomics studies. In nuclear magnetic resonance (NMR) investigations, resonance overlap often hinders unambiguous database matching or de novo compound identification.
Chaevien S Clendinen +6 more
doaj +1 more source
Backbone chemical shift assignments of human 14-3-3$\sigma$ [PDF]
, 2019 14-3-3 proteins are a group of seven dimeric adapter proteins that exert their biological function by interacting with hundreds of phosphorylated proteins, thus influencing their sub-cellular localization, activity or stability in the cell.
Boll, Emmanuelle +5 more
core +3 more sources
Journal of the Belgian Society of Radiology, 2011 MRI and MRS are established methodologies for evaluating intracranial lesions. One MR spectral feature suggested for in vivo grading of astrocytic tumours is the apparent myo-Inositol (mI) intensity (ca 3.55ppm) at short echo times, although glycine (gly)
A P Candiota, C Majós, M Julià-Sapé
doaj +1 more source
Rapid prediction of NMR spectral properties with quantified uncertainty [PDF]
, 2018 open access articleAccurate calculation of specific spectral properties for NMR is an important step for molecular structure elucidation. Here we report the development of a novel machine learning technique for accurately predicting chemical shifts of ...
Jonas, Eric, Kuhn, Stefan
core +1 more source
Separations, 2022 As universally known, gas chromatography (GC) coupled with mass spectrometry (MS) allows us to acquire spectra that can be searched in specific databases to attain qualitative information on a peak of interest.
Gemma De Grazia +5 more
doaj +1 more source
Solution structure of the inner DysF domain of myoferlin and implications for limb girdle muscular dystrophy type 2b [PDF]
, 2008 Mutations in the protein dysferlin, a member of the ferlin family, lead to limb girdle muscular dystrophy type 2B and Myoshi myopathy. The ferlins are large proteins characterised by multiple C2 domains and a single C-terminal membrane-spanning helix ...
Achanzar +70 more
core +1 more source
Challenges in the decomposition of 2D NMR spectra of mixtures of small molecules.
Faraday discussions, 2019 Analytical methods for mixtures of small molecules require specificity (is a certain molecule present in the mix?) and speciation capabilities. NMR spectroscopy has been a tool of choice for both of these issues since its early days, due to its ...
A. Cherni +6 more
semanticscholar +1 more source
Nuclear Magnetic Resonance seq (NMRseq): A New Approach to Peptide Sequence Tags
Toxins, 2018 Structural analysis of peptides with nuclear magnetic resonance (NMR) spectroscopy generally relies on knowledge of the primary sequence to enable assignment of the resonances prior to determination of the three-dimensional structure.
David Wilson, Norelle L. Daly
doaj +1 more source
High-pressure NMR spectroscopy in studies of the conformational composition of small molecules of ibuprofen in supercritical carbon dioxide [PDF]
, 2020 An experimental approach in conducting NMR measurements at supercritical parameters of state is discussed. A novel design of the high-pressure NMR cell was developed which allowed eliminating the field inhomogeneity and, thus, increasing the sensitivity of the experiment at the supercritical state.
arxiv +1 more source
Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding [PDF]
, 2009 The AU-rich element (ARE)-mediated mRNA-degradation activity of the RNA binding K-homology splicing regulator protein (KSRP) is regulated by phosphorylation of a serine within its N-terminal KH domain (KH1).
Briata, Paola +9 more
core +2 more sources