Results 111 to 120 of about 340,947 (357)

Ligand-Directed Acid-Sensitive Amidophosphate 5‑Trifluoromethyl-2′-Deoxyuridine Conjugate as a Potential Theranostic Agent [PDF]

, 2013
Herein, we report a novel strategy to engineer an acid-sensitive anticancer theranostic agent using a vector− drug ensemble. The ensemble was synthesized by directly conjugating the linoleic acid (LA)-modified branched polyethyleneimine with a ...
Godovikova, T.S., NMR Spectroscopy, Kaptein, R., Silnikov, V.N., Sub NMR Spectroscopy, et al., [No Value]   +5 more
core   +1 more source

1H nuclear magnetic resonance spectroscopy (1H NMR) ()

Bäuerle, Peter
  +6 more sources

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

Investigating the assembly and dynamics of the β-barrel assembly machinery in lipid environments with solid-state NMR [PDF]

, 2018
The β-barrel assembly machinery (BAM) complex is an essential machinery in E. coli which is responsible for the correct folding and insertion of outer membrane β-barrel proteins into the outer membrane.
NMR Spectroscopy, Sub NMR Spectroscopy, de Agrela Pinto, C.   +2 more
core  

The eNMR platform for structural biology [PDF]

, 2009
The e-NMR project is a European cooperation initiative that aims at providing the bio-NMR user community with a software platform integrating and streamlining the computational approaches necessary for the analysis of bio-NMR data.
NMR Spectroscopy, Rosato, Antonio, Antonio Rosato, Alexandre M. J. J. Bonvin, Sub NMR Spectroscopy, Tsjerk A. Wassenaar, Wassenaar, T.A., Bonvin, A.M.J.J., Rosato, A.   +8 more
core   +1 more source

Remarkable functions of sn-3 hydroxy and phosphocholine groups in 1,2-diacyl-sn-glycerolipids to induce clockwise (+)-helicity around the 1,2-diacyl moiety: Evidence from conformation analysis by ¹H NMR spectroscopy [PDF]

, 2017
Yoshihiro Nishida, Mengfei Yuan, Kazuo Fukuda, Kaito Fujisawa, Hirofumi Dohi, Hirotaka Uzawa   +5 more
openalex   +1 more source

HOF‐Stabilized Apple EV Nanocargo in an NIR‐Responsive Hydrogel Enables On‐Demand Therapeutic Modulation for Transdermal Deep‐Joint Osteoarthritis Therapy

Advanced Healthcare Materials, EarlyView.
An NIR‐responsive transdermal hydrogel integrating apple EV nanocargo, berberine, piperine, HOFs, and graphene oxide enables localized osteoarthritis modulation. The platform supports enhanced transdermal delivery together with mild hyperthermia‐associated and redox‐related responses, leading to reduced inflammation and oxidative stress, improved ...
Yu‐Wen Tseng, Pei‐Wei Weng, Hsien‐Tsung Lu, Jiunn‐Horng Kang, Lekha Rethi, Lekshmi Rethi, Yan‐Ting Chen, Hieu Trung Nguyen, Yao‐Tung Tsai, Andrew E.‐Y. Chuang   +9 more
wiley   +1 more source

Staufen2-mediated RNA recognition and localization requires combinatorial action of multiple domains

Nature Communications, 2019
The Staufen family of RNA-binding proteins are conserved microtubule dependent mRNA transporter factors. Here the authors use biochemical and functional approaches to characterize the RNA-binding properties of mouse Staufen 2 and study the mRNA binding ...
Simone Heber, Imre Gáspár, Jan-Niklas Tants, Johannes Günther, Sandra M. Fernandez Moya, Robert Janowski, Anne Ephrussi, Michael Sattler, Dierk Niessing   +8 more
doaj   +1 more source

Temperature dependence of the magnetic volume susceptibility of human breast fat tissue: an NMR study [PDF]

, 2012
Object Proton resonance frequency shift (PRFS)-based MR thermometry (MRT) is hampered by heat-induced susceptibility changes when applied in tissues containing fat, e.g., the human breast.
NMR Spectroscopy, Bakker, C.J.G., Bartels, L.W., Ippel, J.H., Sub NMR Spectroscopy, Boelens, R., Sprinkhuizen, S.M., Viergever, M.A.   +7 more
core   +1 more source

Affinity‐Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

Advanced Healthcare Materials, EarlyView.
Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He, Nicholas L. Fletcher, Gayathri R. Ediriweera, Yifei Zhu, James Humphries, Christopher B. Howard, Jiazheng Wang, Craig A. Bell, Kristian Kempe, Kristofer J. Thurecht   +9 more
wiley   +1 more source