Results 301 to 310 of about 566,413 (348)
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Annual Review of Physiology, 1992
The NMR experiments on isolated cell preparations (5, 23, 31) afford control over physiological and biochemical variables that are not under experimental control in intact animals, or in perfused organ systems. For intact tissues, the use of defined cell preparations solves (or circumvents) the problem of spatial localization, which has posed a ...
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The NMR experiments on isolated cell preparations (5, 23, 31) afford control over physiological and biochemical variables that are not under experimental control in intact animals, or in perfused organ systems. For intact tissues, the use of defined cell preparations solves (or circumvents) the problem of spatial localization, which has posed a ...
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Biochemistry, 2001
The recent development of "in-cell NMR" techniques by two independent groups has demonstrated that NMR spectroscopy can be used to characterize the conformation and dynamics of biological macromolecules inside living cells. In this article, we describe different methods and discuss current and future applications as well as critical parameters of this ...
Z, Serber, V, Dötsch
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The recent development of "in-cell NMR" techniques by two independent groups has demonstrated that NMR spectroscopy can be used to characterize the conformation and dynamics of biological macromolecules inside living cells. In this article, we describe different methods and discuss current and future applications as well as critical parameters of this ...
Z, Serber, V, Dötsch
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Indirect Covariance NMR Spectroscopy
Journal of the American Chemical Society, 2004A novel NMR scheme is presented that establishes homonuclear spin correlations without requiring direct detection of the spin species. This covariance NMR method is experimentally demonstrated for a mixture of amino acids and for the uniformly 13C-labeled cyclic decapeptide antamanide using a 13C-edited TOCSY experiment. The method opens up new avenues
Fengli, Zhang, Rafael, Brüschweiler
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2005
The role of a protein inside a cell is determined by both its location and its conformational state. Although fluorescence techniques are widely used to determine the cellular localization of proteins in vivo, these approaches cannot provide detailed information about a protein's three-dimensional state.
Zach, Serber +3 more
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The role of a protein inside a cell is determined by both its location and its conformational state. Although fluorescence techniques are widely used to determine the cellular localization of proteins in vivo, these approaches cannot provide detailed information about a protein's three-dimensional state.
Zach, Serber +3 more
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1990
In vivo nuclear magnetic resonance (NMR) spectroscopy has an assured role to play in medical research because it enables one to interrogate non-invasively a range of biochemical processes, both in the resting state and then serially when they are changing in response to some induced stress.
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In vivo nuclear magnetic resonance (NMR) spectroscopy has an assured role to play in medical research because it enables one to interrogate non-invasively a range of biochemical processes, both in the resting state and then serially when they are changing in response to some induced stress.
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