Results 91 to 100 of about 21,644,340 (278)
Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening
Advanced Science, EarlyView.Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun +6 more
wiley +1 more source
“ALL I CAN DO IS THE WORST I CAN DO” - Male Fear and the Backlash in Stephen King´s Misery [PDF]
The horror trope of sexual violence against women emerges as a result of the backlash of second wave feminism and embodies the collective patriarchal fantasy of violence against women and the patriarchal fear of female liberation.
Nyby, No
core +1 more source
Revista Direitos Humanos e DemocraciaEste artigo tem por objetivo geral analisar a PEC nº 48/2023, além do entendimento do STF, no julgamento do RE nº 1017365, de modo a verificar se a tese do marco temporal se mostra íntegra e coerente com o sistema constitucional vigente.
Marcelino Meleu +2 more
doaj +1 more source
Advanced Science, EarlyView.Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li +4 more
wiley +1 more source
Study on the Tooth Surface Contact Temperature of Spur Gear
Jixie chuandong, 2020 In view of the important influence of tooth surface contact temperature on gear meshing process， the calculation formulas of tooth surface contact temperature of spur gear under four different lubrication conditions are established based on Blok flash ...
Jiazhi Shen, Xiangfeng Gou, Lingyun Zhu
doaj
Design of a Backdrivable Triglide Robot
MATEC Web of Conferences, 2015 The paper presents a novel Triglide robot that gives low inertia and low friction, back-drivability, no backlash, but stiffness in vertical direction. These features give the robot to be a good candidate as a collaborative assembly robot.
Angsupasirikul Natthapong +1 more
doaj +1 more source
Advanced Science, EarlyView.Rod Origami (RodOri) springs harness snap‐through instabilities of pre‐stressed curved rods with geometrically programmable buckling behavior. Integrating RodOri springs with distinct geometries yields multistable metamaterials that undergo stepwise reconfiguration via sequential snapping, achieving wide‐range tunability of stiffness and resonance ...
Jeseung Lee +2 more
wiley +1 more source
Advanced Science, EarlyView.A versatile framework integrates addressable electrothermal actuation and strain‐constraint mechanisms to construct programmable shape‐morphing soft matter systems. By combining an analytical inverse design strategy for high‐fidelity 3D surface reconstruction with deep learning‐based closed‐loop control, this approach enables zero‐energy shape locking,
Kai Liu +5 more
wiley +1 more source
Advanced Science, EarlyView.A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang +17 more
wiley +1 more source
The global participation backlash: Implications for natural resource initiatives [PDF]
, 2017 Civil society organizations can help to ensure good governance over natural resources as members of global multi-stakeholder initiatives like the Extractive Industries Transparency Initiative.
Dupuy, Kendra
core