Results 31 to 40 of about 9,677 (255)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Energy absorption device Patent [PDF]

open access: yes, 1966
Energy absorption device in high precision gear train for protection against damage to components caused by stop ...
Fredrickson, C. A.
core   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Nutation Damper System [PDF]

open access: yes, 1983
The Nutation Damper System is a three function mechanism designed for the Galileo Spacecraft, a spin stabilized deep-space probe to Jupiter. By damping the movement of a large deployable science boom acting as an outboard pendulum, the nutation damper ...
Sevilla, D. R.
core   +1 more source

Cost‐Effectiveness of Low‐Dose Colchicine Prophylaxis When Starting Allopurinol Using the “Start‐Low Go‐Slow” Approach for Gout: Evidence From a Noninferiority Randomized Double‐Blind Placebo‐Controlled Trial

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to investigate the cost‐effectiveness of low‐dose colchicine prophylaxis for preventing gout flares when starting allopurinol using the “start‐low go‐slow” approach. Methods Participants with gout, fulfilling the American College of Rheumatology recommendations for starting urate‐lowering therapy and with serum urate
Yana Pryymachenko   +4 more
wiley   +1 more source

STUDY OF MECHANICAL IMBALANCE AT A HYDRO-AGGREGATE WITH KAPLAN TURBINE [PDF]

open access: yesAnalele Universităţii "Constantin Brâncuşi" din Târgu Jiu: Seria Inginerie, 2019
In present paper we have conducted an experimental study regarding mechanical imbalance of hydro-aggregate from CHE Mănicești, having Kaplan turbine. Before disassembling the structure, we have noticed high vibrations when functioning with no excitation ...
C. Haţiegan   +3 more
doaj  

“Emenda da vaquejada”: Efeito backlash e o controle de constitucionalidade da emenda constitucional nº 96/2017

open access: yesRevista do Direito Público, 2021
A prática da vaquejada foi objeto de ação direta de inconstitucionalidade no ano de 2016 no Supremo Tribunal Federal. Nesta ação o STF decidiu pela inconstitucionalidade de lei estadual que regulamentava a prática.
Mateus Gunnar Marques da Silva   +1 more
doaj   +1 more source

Transfer of Energy and Momentum Between Magnetoactive Surface Microstructure and a Solid Object

open access: yesAdvanced Engineering Materials, EarlyView.
We demonstrate that magnetoactive multilamellar arrays subjected to a rotating magnetic field can function as platforms for controlled transport of physical objects. Through systematic experimental investigation, we elucidate the underlying physical mechanisms determining the upper limit of the achievable transportation speed in such magnetic “conveyor‐
Arne Geldof   +9 more
wiley   +1 more source

Dual arm master controller development [PDF]

open access: yes, 1985
The advanced servomanipulator (ASM) slave was designed with an anthropomorphic stance gear/torque tube power drives, and modular construction. These features resulted in increased inertia, friction, and backlash relative to tape driven manipulators ...
Kuban, D. P., Perkins, G. S.
core   +1 more source

CRISPR/Cas9‐Assisted Microrobots for Fast and Ultrasensitive “On‐The‐Fly” Next‐Generation DNA Detection

open access: yesAdvanced Functional Materials, EarlyView.
This work presents self‐propelled CRISPR/Cas9‐functionalized Au–MRs for rapid, amplification‐free, “on‐the‐fly” DNA detection. By harnessing motion‐assisted signal recovery, the platform achieved the limit of detection in low fM DNA concentrations, enabling detection across a wide dynamic range within only 5 min, which is significantly faster than any ...
Jyoti   +3 more
wiley   +1 more source

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