Results 11 to 20 of about 19,323,977 (168)

Association of matrix metalloproteinase‐9 and nitric oxide with hypertension in obstructive sleep apnea

Laryngoscope Investigative Otolaryngology, Volume 7, Issue 3, Page 885-893, June 2022., 2022
Abstract Background Patients with obstructive sleep apnea (OSA) are more likely to suffer from hypertension. At the same time, the serum levels of matrix metalloproteinase‐9 (MMP‐9) and nitric oxide (NO) in patients with OSA are also changed in OSA patients.
Shiying Zeng, Shisheng Li, Qinglai Tang, Ayinuer Tuerdi, Xinying Tong, Xiaojun Tang, Danhui Yin, Mengmeng Li, Qian Yang   +8 more
wiley   +1 more source

Novel soluble guanylyl cyclase activators increase glomerular cGMP, induce vasodilation and improve blood flow in the murine kidney

British Journal of Pharmacology, Volume 179, Issue 11, Page 2476-2489, June 2022., 2022
Background and Purpose Generation of cGMP via NO‐sensitive soluble guanylyl cyclase (sGC) has been implicated in the regulation of renal functions. Chronic kidney disease (CKD) is associated with decreased NO bioavailability, increased oxidative stress and oxidation of sGC to its haem‐free form, apo‐sGC.
Daniel Stehle, Min Ze Xu, Tibor Schomber, Michael G. Hahn, Frank Schweda, Susanne Feil, Jan R. Kraehling, Frank Eitner, Andreas Patzak, Peter Sandner, Robert Feil, Agnès Bénardeau   +11 more
wiley   +1 more source

Effect of 8 Weeks of Aerobic Training Combined with Vitamin D Supplementation on Nitric Oxide and Endothelin- 1 in Patients with Hypertension [PDF]

Research in Molecular Medicine, 2023
Background: This study aimed to investigate the effect of 8 weeks of aerobic exercise combined with vitamin D supplementation on nitric oxide (NO) and endothelin-1 (ET-1) in patients with hypertension.
Mozaffar Jan faza, Mohammad Rahman Rahimi, Roghaiyeh afsargharehbagh, Nasser Rostamzadeh   +3 more
doaj  

Multidrug resistance proteins preferentially regulate natriuretic peptide‐driven cGMP signalling in the heart and vasculature

British Journal of Pharmacology, Volume 179, Issue 11, Page 2443-2459, June 2022., 2022
Background and Purpose cGMP underpins the bioactivity of NO and natriuretic peptides and is key to cardiovascular homeostasis. cGMP‐driven responses are terminated primarily by PDEs, but cellular efflux via multidrug resistance proteins (MRPs) might contribute.
Robert M. H. Grange, Michael E. J. Preedy, Aniruthan Renukanthan, Joshua P. Dignam, Vanessa J. Lowe, Amie J. Moyes, Cristina Pérez‐Ternero, Aisah A. Aubdool, Reshma S. Baliga, Adrian J. Hobbs   +9 more
wiley   +1 more source

Reduction of NO production in LPS-stimulated primary rat microglial cells by Bromelain [PDF]

Journal of Cell and Molecular Research, 2011
Microglia, the sentries of the brain, is highly implicated in neurodegeneration as in neuroprotection. Chronic microglial activation endangers neuronal survival through the release of various potentially neurotoxic mediators including Nitric Oxide (NO ...
Soraya Abbasi Habashi, Farzaneh Sabouni, Ali Moghimi, Saeed Ansari Majd, Azita Parvaneh Tafreshi   +4 more
doaj   +1 more source

Relationship between longitudinal changes in type‐2 inflammation, immunoglobulin E sensitization, and clinical outcomes in young asthmatics

Clinical and Translational Allergy, Volume 11, Issue 7, September 2021., 2021
Abstract Background Asthma is a heterogeneous condition where biomarkers may be of considerable advantage in diagnosis and therapy monitoring. However, the changes in asthma biomarkers and immunoglobulin E (IgE) over the course of life has not been extensively investigated. Objective To study longitudinal changes in type‐2 inflammatory biomarkers, IgE,
Nikolaos Tsolakis, Tiago Jacinto, Christer Janson, Magnus Borres, Andrei Malinovschi, Kjell Alving   +5 more
wiley   +1 more source

Loss of NO(g) to painted surfaces and its re‐emission with indoor illumination

Indoor Air, Volume 31, Issue 2, Page 566-573, March 2021., 2021
Abstract Heterogeneous surface reactions play a key role in the chemistry of the indoor environment because of the large indoor surface‐to‐volume ratio. The presence of photocatalytic material in indoor paints may allow photochemical reactions to occur at wavelengths of light that are present indoors.
Stephanie H. Jones, Florian P. R. Hosse, Xiaoying Yang, D. James Donaldson   +3 more
wiley   +1 more source

Measuring on-Road Vehicle Hot Running NO_x Emissions with a Combined Remote Sensing–Dynamometer Study

Atmosphere, 2020
This study explores the correlation in measured hot running NO/CO2 ratios by a remote sensing device (RSD) and dynamometer testing. Two large diesel cars (E4/E5) are tested on the dynamometer in hot running conditions using a new drive cycle developed ...
Robin Smit, Daniel Kennedy
doaj   +1 more source

BuyangHuanwu Decoction attenuates cerebral vasospasm caused by subarachnoid hemorrhage in rats via PI3K/AKT/eNOS axis

Open Life Sciences, 2022
The ancient Chinese remedy BuyangHuanwu Decoction (BHD) is used to treat qi deficit and blood stasis conditions. This work investigated the effect of BHD on cerebral vasospasm (CVS) caused by subarachnoid hemorrhage (SAH).
Li Weiping, Wang Ru, Huang Wei, Shen Yanfang, Du Jumei, Tian Ye   +5 more
doaj   +1 more source

Different Macrophage Type Triggering as Target of the Action of Biologically Active Substances from Marine Invertebrates

Marine Drugs, 2020
Macrophages play a fundamental role in the immune system. Depending on the microenvironment stimuli, macrophages can acquire distinct phenotypes characterized with different sets of the markers of their functional activities.
Lyudmila S. Dolmatova, Igor Yu. Dolmatov   +1 more
doaj   +1 more source