Oxidative Stress and Pteridines in Pediatric Asthma: Relationship to Exhaled Nitric Oxide
Fractional exhaled nitric oxide (FeNO) is a useful marker of airway inflammation in asthmatics. Nitric oxide synthase (NOS) requires tetrahydrobiopterin as a cofactor and produces superoxide during NO generation.
Takeda Taisuke+5 more
doaj +1 more source
Protective Effects of Betanin against Oxidative Stress in a Peripheral Artery Vasospasm Model in Rat
Objective: The aim of this study is to determine protective/modulatory effects of betanin in a femoral artery vasospasm model in rats. Materials and Methods: Sprague-Dawley rats were divided into three groups.
Kevser Tural+5 more
doaj +1 more source
Soluble GC stimulators and activators: Past, present and future
The discovery of soluble GC (sGC) stimulators and sGC activators provided valuable tools to elucidate NO–sGC signalling and opened novel pharmacological opportunities for cardiovascular indications and beyond. The first‐in‐class sGC stimulator riociguat was approved for pulmonary hypertension in 2013 and vericiguat very recently for heart failure.
Peter Sandner+7 more
wiley +1 more source
Identifying and analyzing the factors affecting on urban sprawl (Case Study: Ahvaz City)
Identifying effective mechanisms and urban expansion forces is an important step for better understanding of the spatial pattern, process and consequences of urban expansion that it is essential for planning and urban growth policies and sustainable urban development.
ahmad poorahmad+3 more
openaire +1 more source
GROWING UP IN IRELAND. KEY FINDINGS: COHORT ’08 AT 9 YEARS OLD. NO. 3 HEALTH AND PHYSICAL DEVELOPMENT. Cohort '08 November 2018 [PDF]
This series of Key Findings draws on information provided by the Cohort ‘08 9-year-old and his or her Primary Caregiver (usually the mother, and henceforth in this report referred to as the mother).
Author, No
core
Polyamines: pleiotropic molecules regulating plant development and enhancing crop yield and quality
Summary Polyamines (PAs) are pleiotropic bioorganic molecules. Cellular PA contents are determined by a balance between PA synthesis and degradation. PAs have been extensively demonstrated to play vital roles in the modulation of plant developmental processes and adaptation to various environmental stresses.
Haishan Yang+5 more
wiley +1 more source
Cell toxicity mechanism and biomarker
AbstractCell toxicity may result in organ dysfunction and cause severe health problem. Recent studies revealed many toxicants may induced the over production of Nitric oxide, reactive oxygen species and the subsequent oxidative stress, cause cell toxicity.
Yong Zhang
wiley +1 more source
GROWING UP IN IRELAND KEY FINDINGS: COHORT ’98 AT 20 YEARS OLD IN 2018/19 NO. 3 SOCIO-EMOTIONAL WELL-BEING AND KEY RELATIONSHIPS AT AGE 20 [PDF]
This Key Findings report presents summary information on the lives and circumstances of the 20-year-olds from the fourth wave of interviews with Growing Up in Ireland’s older Cohort ’98 between August 2018 and June 2019.
Author, No
core
English polar particles yes and no are interchangeable in response to negative sentences, that is, either one can be used to convey both positive and negative responses.
Daniel Goodhue, Michael Wagner
doaj +2 more sources
The effects of simvastatin‐loaded nanoliposomes on human multilineage liver fibrosis microtissue
Abstract In this in vitro study, for the first time, we evaluate the effects of simvastatin‐loaded liposome nanoparticles (SIM‐LipoNPs) treatment on fibrosis‐induced liver microtissues, as simvastatin (SIM) has shown potential benefits in the non‐alcoholic fatty liver disease process.
Shima Parsa+10 more
wiley +1 more source